Chemical constituents of the suspension cell cultures of Maytenus hookeri

	Chemical constituents of the suspension cell cultures of Maytenus hookeri
	Lu, CH ; Zhang, JX ; Gan, FY ; Shen, YM
刊名	ACTA BOTANICA SINICA
	2002-05-01
卷号	44 期号:5 页码:603-610
关键词	Maytenus hookeri Celastraceae suspension cell cultures maytansine 2 3-diacetoxyl maytenusone
ISSN号	0577-7496
英文摘要	Suspension cell cultures of Maytenus hookeri Loos. (Celastraceae) in SH media were established from the calli induced from the leaves and young steins of M. hookeri on MS media with the supplement of 2 mg/L 2,4-D and 0.1 mg/L KIN (kinetin). Ethyl acetate extract of the cultures showed inhibitory activities against Penicillium avellaneum UC-4376 which was sensitive to maytansinoids. Exhaustive isolation of natural products from a large scale of suspension cell cultures did not yield maytansine instead of affording nine compounds including one novel triterpenoid, named 2, 3-diacetoxyl maytenusone (1), and eight known ones including squalene (2), beta-sitosterol (3), 2', 3', 4-triacetyl-sitoindoside I (4), salaspermic acid (5), maytenonic acid (6), 2alpha-hydroxy-maytenonic acid (7), 6, 11,12-trihydroxy-8, 11, 13-abietrien-7-one (8) and 11, 12-dihydroxy-8, 11, 13-abietatrien-7-one (9) elucidated on the basis of 1D and 2D NMR data. The H-1-NMR and C-13-NMR assignments were made for 1, 5, 6 and 7, while the C-13-NMR assignments for 5 and 6 were revised. The chemical results suggested that the suspension cell cultures of M. hookeri did not produce maytansinoids under the reported experiment conditions.
学科主题	Biochemistry & Molecular Biology; Plant Sciences
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	TRIPTERYGIUM-WILFORDII ; SALASPERMIC ACID ; TRITERPENES ; DITERPENOIDS ; CANARIENSIS ; ANSAMITOCIN ; INHIBITORS ; AGENTS ; ROOTS ; P-3
收录类别	SCI
语种	英语
WOS记录号	WOS:000175739000018
公开日期	2012-07-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/14211]
专题	昆明植物研究所_离退休
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Key Lab Nat Prod Chem Guizhou Prov, Guiyang 550002, Peoples R China 3.Acad Sinica, Guiyang 550002, Peoples R China
推荐引用方式 GB/T 7714	Lu, CH,Zhang, JX,Gan, FY,et al. Chemical constituents of the suspension cell cultures of Maytenus hookeri[J]. ACTA BOTANICA SINICA,2002,44(5):603-610.
APA	Lu, CH,Zhang, JX,Gan, FY,&Shen, YM.(2002).Chemical constituents of the suspension cell cultures of Maytenus hookeri.ACTA BOTANICA SINICA,44(5),603-610.
MLA	Lu, CH,et al."Chemical constituents of the suspension cell cultures of Maytenus hookeri".ACTA BOTANICA SINICA 44.5(2002):603-610.