CORC  > 山东大学
Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations
Niu, Yuzhen; Zhang, Yan; Yao, Xiaojun
刊名CHEMICAL BIOLOGY & DRUG DESIGN
2019
卷号93期号:2页码:177-187
关键词binding free energy calculation BRAF inhibitors drug resistance molecular dynamics simulation residue interaction network analysis
DOI10.1111/cbdd.13399
URL标识查看原文
公开日期[db:dc_date_available]
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/4538938
专题山东大学
作者单位1.Shandong Univ Technol, Sch Life Sci, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo, Peoples R China.
2.Guiyang Coll
推荐引用方式
GB/T 7714
Niu, Yuzhen,Zhang, Yan,Yao, Xiaojun. Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations[J]. CHEMICAL BIOLOGY & DRUG DESIGN,2019,93(2):177-187.
APA Niu, Yuzhen,Zhang, Yan,&Yao, Xiaojun.(2019).Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations.CHEMICAL BIOLOGY & DRUG DESIGN,93(2),177-187.
MLA Niu, Yuzhen,et al."Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations".CHEMICAL BIOLOGY & DRUG DESIGN 93.2(2019):177-187.
个性服务
查看访问统计
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。


©版权所有 ©2017 CSpace - Powered by CSpace