'Non-destructive' biocomputing security system based on gas-controlled biofuel cell and potentially used for intelligent medical diagnostics

	'Non-destructive' biocomputing security system based on gas-controlled biofuel cell and potentially used for intelligent medical diagnostics
	Zhou M ; Zheng XL ; Wang J ; Dong SJ
刊名	bioinformatics
	2011
卷号	27 期号:3 页码:399-404
关键词	MOLECULAR KEYPAD LOCK LOGIC SYSTEMS FUEL-CELLS NETWORKS JUICE GATE
ISSN号	1367-4803
通讯作者	wang j
中文摘要	motivation: biofuel cells (bfcs) based on enzymes and microbes are the promising future alternative sources of sustainable electrical energy under mild conditions (i.e. ambient temperature and neutral ph). by combining the adaptive behavior of bfcs self-regulating energy release with the versatility of biocomputing, we construct a novel gas-controlled biocomputing security system, which could be used as the potential implantable self-powered and 'smart' medical system with the logic diagnosis aim. results: we have demonstrated a biocomputing security system based on bfcs. due to the unique 'reset' reagent of n(2) applied in this work, the prepared biocomputing security system can be reset and cycled for a large number of times with no 'reset' reagent-based 'waste'. this would be advantageous for the potential practical applications of such keypad lock as well as the development of biocomputing security devices. in order to validate the universality of the system and also to harvest energy directly from biofuels with enhanced power output, we replace the glucose with orange juice as the biofuel to operate bfcs-based biocomputing system, which also possesses the function of keypad lock. in addition, by introducing bfcs into the biocomputing security system, the adaptive behavior of the bfcs self-regulating the power release would be an immense advantage of such security keypad lock devices in potential self-powered implantable medical systems. the designed sequence gives the maximum power output and discriminate itself from the rest of the sequences. from this, we find that maximizing the dimensionless ratio of gap versus sd of the power output spectrum (a funnel in power outputs) gives the quantitative optimal design criterion. therefore, our construction here may also provide a practical example and microscopic structural basis for mimicking the real biological network systems and bridge the gaps between the theoretical concepts and experiments important for biomolecular systems and synthetic biology.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000286991300014
公开日期	2012-06-11
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/44850]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zhou M,Zheng XL,Wang J,et al. 'Non-destructive' biocomputing security system based on gas-controlled biofuel cell and potentially used for intelligent medical diagnostics[J]. bioinformatics,2011,27(3):399-404.
APA	Zhou M,Zheng XL,Wang J,&Dong SJ.(2011).'Non-destructive' biocomputing security system based on gas-controlled biofuel cell and potentially used for intelligent medical diagnostics.bioinformatics,27(3),399-404.
MLA	Zhou M,et al."'Non-destructive' biocomputing security system based on gas-controlled biofuel cell and potentially used for intelligent medical diagnostics".bioinformatics 27.3(2011):399-404.