Nano-C(60): A Novel, Effective, Fluorescent Sensing Platform for Biomolecular Detection

	Nano-C(60): A Novel, Effective, Fluorescent Sensing Platform for Biomolecular Detection
	Li HL ; Zhang YW ; Luo YL ; Sun XP
刊名	small
	2011
卷号	7 期号:11 页码:1562-1568
关键词	MOLECULAR BEACONS CARBON NANOTUBES DNA ANALYSIS PROBES HYBRIDIZATION C-60 FULLERENES THROMBIN GRAPHENE OLIGONUCLEOTIDES
ISSN号	1613-6810
通讯作者	sun xp
中文摘要	water-soluble nano-c(60) can serve as a novel, effective, fluorescent sensing platform for biomolecular detection with high sensitivity and selectivity. in this paper, fluorescent detection of dna and thrombin via nano-c(60) is demonstrated for the first time. the principle of the assay lies in the fact that the adsorption of the fluorescently labeled single-stranded dna (ssdna) probe by nano-c(60) leads to substantial fluorescence quenching. in the presence of a target, the biomolecular mutual interaction suppresses this quenching, signaling the existence of the target. this sensing system rivals graphene oxide but is superior to other carbon-structure-based systems. the present method can also achieve multiplex dna detection and withstand the interference from human blood serum.
收录类别	SCI收录期刊论文
语种	英语
公开日期	2012-06-11
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/44587]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Li HL,Zhang YW,Luo YL,et al. Nano-C(60): A Novel, Effective, Fluorescent Sensing Platform for Biomolecular Detection[J]. small,2011,7(11):1562-1568.
APA	Li HL,Zhang YW,Luo YL,&Sun XP.(2011).Nano-C(60): A Novel, Effective, Fluorescent Sensing Platform for Biomolecular Detection.small,7(11),1562-1568.
MLA	Li HL,et al."Nano-C(60): A Novel, Effective, Fluorescent Sensing Platform for Biomolecular Detection".small 7.11(2011):1562-1568.