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	Trace element concentrations in hair of healthy Chinese centenarians
	Li Y. H. ; Yang L. S. ; Wang W. Y. ; Li H. R. ; Lv J. M. ; Zou X. Y.
	2011
关键词	Ageing Centenarians Hair Human health Trace element scalp hair greek centenarians reference values elderly-people population copper blood serum zinc deficiency
英文摘要	Trace element concentrations, as indicators of micronutrient status of healthy centenarians, have not been widely analyzed. This study aimed to assess trace element concentrations in the hair of healthy centenarians. The effects of gender and age on element concentrations were also investigated. Eleven trace elements (Al, Ba, Cd, Cr, Cu, Fe, Mo, Pb, Se, Sr and Zn) in the scalp hair of 107 healthy Chinese centenarians were examined. The overall reference values (RVs) in mg/kg for the hair concentrations of trace elements in centenarians were as follows: Al, 14.95; Ba, 2.68; Cd, 0.06; Cr, 0.59; Cu, 6.21); Fe, 19.37; Mo, 0.50; Pb, 4.64; Se, 0.37; Sr, 4.84; and Zn, 154.37. Data analysis found that only Cu and Zn concentrations show a normal distribution, and there is no significant difference between males and females in any element except Zn. However, the levels of Al, Cd, Cr, Fe, Mo, Pb decrease and the levels of Ba, Cu, Se, Sr, Zn increase with age in the centenarian cohort. Results also revealed that sufficient Zn and Se concentrations as well as low exposure to heavy metals pollution contribute to the longevity of centenarians. The results imply the possibility of manipulating trace element concentrations, especially Zn and Se concentrations in tissues, as a means for therapeutic modality in geriatric disease. (C) 2011 Elsevier B.V. All rights reserved.
出处	Science of the Total Environment
卷	409
期	8
页	1385-1390
收录类别	SCI
语种	英语
ISSN号	0048-9697
内容类型	SCI/SSCI论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/23584]
专题	地理科学与资源研究所_历年回溯文献
推荐引用方式 GB/T 7714	Li Y. H.,Yang L. S.,Wang W. Y.,et al. Trace element concentrations in hair of healthy Chinese centenarians. 2011.

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