Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing

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	Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing
	Yang, XM(杨小敏） ; Liu, Q ; Chen, XL ; Yu, F ; Zhu, ZY（朱智勇）
刊名	CARBOHYDRATE POLYMERS
	2008
卷号	73 期号:3 页码:401
ISSN号	0144-8617
通讯作者	Zhu, ZY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, POB 800-204, Shanghai 201800, Peoples R China
英文摘要	gamma-Irradiation combined with freeze-thawing, i.e. irradiation followed by freeze-thawing and freezc-thawing followed by irradiation, was applied to prepare poly(vinyl alcohol) (PVA)/water soluble chitosan (ws-chitosan) hydrogels for wound dressing. The properties of these hydrogels were investigated and compared to those prepared by freeze-thawing and by irradiation, respectively. Hydrogels made by irradiation followed by freeze-thawing show larger swelling capacity and mechanical strength, higher thermal stability, lower water evaporation rate, and are less turbid than those made by pure freeze-thawing and freeze-thawing followed by irradiation. Hydrogels made by irradiation alone cannot be used as wound dressing due to their poor mechanical strength. SEM results show that the final structure of hydrogels made by combined irradiation and freeze-thawing is mainly determined by the first processing step. It is found that the appropriate amount of ws-chitosan can endow hydrogels with large swelling capacity and mechanical strength. The presence of ws-chitosan provides the hydrogels with good antibacterial activity against Escherichia coli (E. coli). (C) 2008 Elsevier Ltd. All rights reserved.
学科主题	Physics
收录类别	SCI
语种	英语
WOS记录号	WOS:000256500200005
公开日期	2012-04-18
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/7755]
专题	上海应用物理研究所_中科院上海应用物理研究所2004-2010年
推荐引用方式 GB/T 7714	Yang, XM,Liu, Q,Chen, XL,et al. Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing[J]. CARBOHYDRATE POLYMERS,2008,73(3):401.
APA	Yang, XM,Liu, Q,Chen, XL,Yu, F,&Zhu, ZY.(2008).Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing.CARBOHYDRATE POLYMERS,73(3),401.
MLA	Yang, XM,et al."Investigation of PVA/ws-chitosan hydrogels prepared by combined gamma-irradiation and freeze-thawing".CARBOHYDRATE POLYMERS 73.3(2008):401.