Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities
	Mu, Huai-Xue 1,2,3,4; Li, Xue-Sen 1,2,4; Fan, Peng 1,2,4; Yang, Guang-Yu 1,2,3,4; Pu, Jian-Xin3 ; Sun, Han-Dong3 ; Hu, Qiu-Fen 1,2; Xiao, Wei-Lie 3
刊名	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
	2011
卷号	13 期号:5 页码:393-399
关键词	Schisandreae Schisandra rubriflora fruits dibenzocyclooctadiene lignans anti-HIV-1 activity
ISSN号	1028-6020
通讯作者	Hu, QF (reprint author), Yunnan Univ Nationalities, Key Lab Ethn Med Resource Chem, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
英文摘要	Two new dibenzocyclooctadiene lignans, rubrilignans A and B (1, 2), together with 17 known ones, were isolated from the fruits of Schisandra rubriflora. The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-HIV-1 activities and showed weak anti-HIV-1 activity with EC50 values of 2.26 and 1.82g/ml, and therapeutic index values of 35.5 and 18.6, respectively.
学科主题	Plant Sciences; Chemistry; Pharmacology & Pharmacy
类目[WOS]	Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]	SCHIZANDRA-CHINENSIS BAILL ; PROPINQUA-VAR.-PROPINQUA ; ABSOLUTE STRUCTURE ; CONSTITUENTS ; WILSONIANA ; NORTRITERPENOIDS ; TRITERPENOIDS
收录类别	SCI ; IC
资助信息	National Natural Science Foundation of China[30830115, 20802082]; Chinese Academy of Sciences[KSCX1-YW-R-24]; 973 programs[2009CB522300, 2009CB940900]; Young Academic and Technical Leader Rising Foundation of Yunnan Province[2006PY01-47]
语种	英语
WOS记录号	WOS:000290046300002
公开日期	2012-04-10
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/5503]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Univ Nationalities, Key Lab Ethn Med Resource Chem, State Ethn Affairs Commiss, Kunming 650031, Peoples R China 2.Minist Educ, Kunming 650031, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 4.Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China
推荐引用方式 GB/T 7714	Mu, Huai-Xue,Li, Xue-Sen,Fan, Peng,et al. Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(5):393-399.
APA	Mu, Huai-Xue.,Li, Xue-Sen.,Fan, Peng.,Yang, Guang-Yu.,Pu, Jian-Xin.,...&Xiao, Wei-Lie.(2011).Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(5),393-399.
MLA	Mu, Huai-Xue,et al."Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.5(2011):393-399.