A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei

doi:10.1111/anu.12956

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei
	Wang, Yilong 1,2,3; Liu, Mei 1,2; Wang, Baojie 1,2; Jiang, Keyong 1,2; Wang, Mengqiang1,2,4 ; Wang, Lei 1,2,5
刊名	AQUACULTURE NUTRITION
	2019-08-12
页码	13
关键词	aflatoxin B1 hepatopancreas intestinal Litopenaeus vannamei metabolism
ISSN号	1353-5773
DOI	10.1111/anu.12956
通讯作者	Wang, Mengqiang(wangmenggiang@qdio.ac.cn) ; Wang, Lei(wanglei@qdio.ac.cn)
英文摘要	The present study was to determine the time-dependent alterations in growth performance, histomorphology, digestive enzymes activities and the genes expression related to target of rapamycin (TOR) signalling pathway involved in hepatopancreas and intestine of Litopenaeus vannamei at 3, 6, 12, 18, 24 and 30 days after Aflatoxin B1 (AFB1) challenge. The results manifested that AFB1 could induce a significant decrease in growth performance and visible variations of the hepatopancreas and intestine structures in shrimp. Meanwhile, the digestive enzymes activities and genes expression level were significantly lower in the experimental group than in the control group and showed a time-dependent decrease (p < 0.05). The expression levels of tor and s6k were significantly higher in the experimental group than in the control group from days 6 to 24 and showed a tendency to increase first and then decrease as a whole (p < 0.05). Meanwhile, we analysed candidate pathways involved in hepatopancreas and intestine of shrimp in metabolic response to AFB1. The mainly disturbed pathways related to metabolism in hepatopancreas were involved in pyrimidine, glycosylphosphatidylinositol, glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism, while the mainly disturbed metabolic pathways in intestine were glycosaminoglycan, vitamin and amino acid biosynthesis and metabolism.
资助项目	Major Scientific and Technological Innovation Project, Shandong Province, China[2018SDKJ0502-2] ; Science and Technology Development Fund Project of Shinan District, Qingdao City, China[2018-4-001-ZH]
WOS研究方向	Fisheries
语种	英语
出版者	WILEY
WOS记录号	WOS:000481032400001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/162348]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Wang, Mengqiang; Wang, Lei
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Natl Lab Marine Sci & Technol, Res Platform Marine Mol Biotechnol, Qingdao, Shandong, Peoples R China 5.Chinese Acad Sci, CAS Ctr Ocean Mega Sci, Qingdao, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yilong,Liu, Mei,Wang, Baojie,et al. A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei[J]. AQUACULTURE NUTRITION,2019:13.
APA	Wang, Yilong,Liu, Mei,Wang, Baojie,Jiang, Keyong,Wang, Mengqiang,&Wang, Lei.(2019).A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei.AQUACULTURE NUTRITION,13.
MLA	Wang, Yilong,et al."A global view of hepatopancreas and intestinal reveals the potential influencing mechanism of aflatoxin B1 on nutrition and metabolism in Litopenaeus vannamei".AQUACULTURE NUTRITION (2019):13.