Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging

doi:10.1039/c8nj04208j

CORC > 近代物理研究所 > 中国科学院近代物理研究所 > 兰州重离子研究装置

	Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging
	Ma, Jianlong; Li, Feifei; Li, Qiang; Li, Yijing; Yan, Chaoxian; Lu, Xiaofeng; Guo, Yong
刊名	NEW JOURNAL OF CHEMISTRY
	2018
卷号	42 页码:19272-19278
ISSN号	1144-0546
DOI	10.1039/c8nj04208j
英文摘要	Hydrogen sulfide (H2S) is a remarkable endogenous gasotransmitter involved in numerous biological processes, and its noninvasive, rapid and accurate measurement in living cells and animals is urgently needed. Herein, we report a ratiometric fluorescent H2S-specific probe (CyT). This new probe can be readily prepared by modifying the triflate group (CF3SO3-) into hemicyanine, and it shows excellent sensing properties. First, CyT is highly selective against other biologically relevant anions, cations, reactive sulfur and small molecules; meanwhile, it has a low limit of detection (LOD) to H2S (7.33 nM) In addition, CyT exhibits rapid response to H2S (rate constant is 1464 M-1 s(-1)) and apparent color change from dark blue to very pale green, which is observed with the naked-eye. Furthermore, it exhibits low cytotoxicity to HeLa cells and can be successfully used for the detection of H2S activity in cells and zebrafish.
WOS记录号	WOS:000451074200085
内容类型	期刊论文
源URL	[http://119.78.100.186/handle/113462/59883]
专题	近代物理研究所_兰州重离子研究装置近代物理研究所_生物物理研究室
推荐引用方式 GB/T 7714	Ma, Jianlong,Li, Feifei,Li, Qiang,et al. Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging[J]. NEW JOURNAL OF CHEMISTRY,2018,42:19272-19278.
APA	Ma, Jianlong.,Li, Feifei.,Li, Qiang.,Li, Yijing.,Yan, Chaoxian.,...&Guo, Yong.(2018).Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging.NEW JOURNAL OF CHEMISTRY,42,19272-19278.
MLA	Ma, Jianlong,et al."Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging".NEW JOURNAL OF CHEMISTRY 42(2018):19272-19278.