A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis

doi:10.1016/j.marpolbul.2016.10.032

	A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis
	Zhang, Jing 1; Wang, You 1; Sun, Kai-Ming 2; Fang, Kuan 1; Tang, Xuexi 1
刊名	MARINE POLLUTION BULLETIN
	2016-12-15
卷号	113 期号:1-2 页码:408-413
关键词	Polybrominated diphenyl ethers (PBDEs) Rotifer Reactive oxygen species (ROS) Calcium ion (Ca2+) Oxidative stress
ISSN号	0025-326X
DOI	10.1016/j.marpolbul.2016.10.032
英文摘要	Polybrominated diphenyl ethers (PBDEs) are widely dispersed persistent organic pollutants in the marine ecosystem. However, their toxic mechanisms in marine organisms, especially invertebrates, remain poorly understood. Two common congeners of PBDEs, tetrabrominated diphenyl ether-47 (BDE-47) and decabrominated diphenyl ether-209 (BDE-209), were investigated. Their toxic mechanisms, with a focus on oxidative stress, were examined in rotifer Brachionus plicatilis. Overproduction of reactive oxygen species (ROS) was induced by two PBDEs. The expression of superoxide dismutase (SOD) mRNA was increased, suggesting SOD play a main role in ROS-scavenging. The intercellular concentrations of calcium (ICa2+](in)) and the expression of calmodulin (CaM) mRNA were increased. This indicates the calcium ion (Ca2+) signaling channel is involved in PBDEs stress. Further analysis showed that the reproductive system might be the target site for toxicity of PBDEs. Moreover, high value of detection indexes in BDE-47 experimental groups suggested BDE-47 might cause higher oxidative damage than BDE-209 in rotifers. (C) 2016 Elsevier Ltd. All rights reserved.
资助项目	NSFC-Shandong Joint Fund[U1406403]
WOS关键词	ANTIOXIDANT DEFENSE SYSTEM ; IN-VITRO ; CARASSIUS-AURATUS ; BDE-47 ; CALCIUM ; APOPTOSIS ; CELLS ; BDE-209 ; MECHANISM ; DYSFUNCTION
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000390734600069
内容类型	期刊论文
源URL	[http://ir.fio.com.cn:8080/handle/2SI8HI0U/26372]
专题	自然资源部第一海洋研究所
通讯作者	Wang, You; Tang, Xuexi
作者单位	1.Ocean Univ China, Coll Marine Life Sci, Dept Marine Ecol, Qingdao 266003, Peoples R China 2.State Ocean Adm, Inst Oceanog 1, Qingdao 266061, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Jing,Wang, You,Sun, Kai-Ming,et al. A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis[J]. MARINE POLLUTION BULLETIN,2016,113(1-2):408-413.
APA	Zhang, Jing,Wang, You,Sun, Kai-Ming,Fang, Kuan,&Tang, Xuexi.(2016).A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis.MARINE POLLUTION BULLETIN,113(1-2),408-413.
MLA	Zhang, Jing,et al."A study of oxidative stress induced by two polybrominated diphenyl ethers in the rotifer Brachionus plicatilis".MARINE POLLUTION BULLETIN 113.1-2(2016):408-413.