Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress

doi:10.1016/j.marpolbul.2017.01.015

	Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress
	Jian, Xiaoyang 1; Tang, Xuexi 1; Xu, Ningning 1; Sha, Jingjing 2; Wang, You 1
刊名	MARINE POLLUTION BULLETIN
	2017-03-15
卷号	116 期号:1-2 页码:298-306
关键词	2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) Xenobiodc-metabolizing enzymatic system Antioxidant enzymatic system Reactive oxygen species (ROS) Marine zooplankton Brachionus plicatilis
ISSN号	0025-326X
DOI	10.1016/j.marpolbul.2017.01.015
英文摘要	A series short-term toxicological tests were conducted on the rotifer Brachionus plicatilis to assess the toxicity of the flame retardant 2,2',4,4'-tetrabrominated biphenyl ether (BDE-47). BDE-47 increased mortality, morphological damage, and altered population dynamics and fecundity of rotifer. Antioxidant enzymes were differentially changed to maintain the balance between antioxidant and pro-oxidant activity. However, with increases in the concentration of BDE-47, the metabolic and antioxidant activity decreased. Moreover, the reactive oxygen species (ROS) and malondialdehyde contents increased and the ratio between glutathione and glutathione-SH decreased, indicating oxidative stress. The addition of the ROS-inhibitor N-acetylcysteine alleviated the degree of damage and stimulated the activity of xenobiotic-metabolizing and antioxidant system, which suggested that ROS were the most important loop in the stress response. (C) 2017 Elsevier Ltd. All rights reserved.
资助项目	NSFC-Shandong Joint Fund[W406403]
WOS关键词	POLYBROMINATED DIPHENYL ETHERS ; POPULATION DEMOGRAPHIC PARAMETERS ; SHRIMP LITOPENAEUS-VANNAMEI ; ZEBRAFISH DANIO-RERIO ; ENZYME-ACTIVITIES ; ASSESS IMPACTS ; PBDE MIXTURE ; EXPOSURE ; TOXICITY ; BIOACCUMULATION
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000399507600046
内容类型	期刊论文
源URL	[http://ir.fio.com.cn:8080/handle/2SI8HI0U/25081]
专题	自然资源部第一海洋研究所
通讯作者	Wang, You
作者单位	1.Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Shandong, Peoples R China 2.State Ocean Adm, North China Sea Environm Monitoring Ctr, Fushun Rd 22, Qingdao 266033, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Jian, Xiaoyang,Tang, Xuexi,Xu, Ningning,et al. Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress[J]. MARINE POLLUTION BULLETIN,2017,116(1-2):298-306.
APA	Jian, Xiaoyang,Tang, Xuexi,Xu, Ningning,Sha, Jingjing,&Wang, You.(2017).Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress.MARINE POLLUTION BULLETIN,116(1-2),298-306.
MLA	Jian, Xiaoyang,et al."Responses of the rotifer Brachionus plicatilis to flame retardant (BDE-47) stress".MARINE POLLUTION BULLETIN 116.1-2(2017):298-306.