Trace element characteristics of a Gorham-Stout Syndrome sufferer | |
Chen, M (Chen Ming); Cao, XJ (Cao XiaoJuan); Mayouma, L (Mayouma, Loumouamou); Lu, XF (Lu XiaoFeng); Jacques, Y (Jacques Yvon); Feng, L (Feng Liu) | |
刊名 | CHINESE SCIENCE BULLETIN
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2008 | |
卷号 | 53期号:9页码:1388-1392 |
关键词 | endemic disease trace element geochemistry hair analysis Gorham-Stout syndrome |
ISSN号 | 1001-6538 |
英文摘要 | Gorham-Stout Syndrome (GSS) is an infrequent and mysterious bone disease characterized by massive bone dissolving or even disappearing due to an unknown pathogeny. It is quite different from the Itai-itai disease and osteoporosis. In 2001, an 8-year-old boy from a small town in Xinjiang was found to get GSS disease. Some parts of his bones vanished without any external force. Results showed that the concentrations of Cd and Cu, especially Na and K in his hair were far higher than those of the healthy people, and the concentration of Cd was 2 times that of the reference while those of Cr and Zn were insufficient for health. The ratio of K/Na was also higher than that of healthy group. Four different ratios revealed weak bone growth potential and strong bone breakage occurred simultaneously in the GSS sufferer's skeletal system. It might be the synergistic effect of the trace elements leading to the baffling syndrome. Further investigation demonstrated that the trace elements can cause a series of diseases, including GSS disease and a typical rheumatoid arthritis (ARA). Epidemiological investigation also proved that there were about 25% of the inhabitants in the town suffered from an ARA. All of these data implied there was significant relationship among Gorham-Stout Syndrome, ARA and prolapse of lumbar intervertebral disc. |
学科主题 | 地球化学 |
WOS研究方向 | Science & Technology - Other Topics |
语种 | 英语 |
出版者 | SCIENCE PRESS |
WOS记录号 | WOS:000255985700016 |
内容类型 | 期刊论文 |
源URL | [http://119.78.100.197/handle/2HKVOGP0/38627] ![]() |
专题 | 中国地质调查局 |
作者单位 | Beijing Univ Chem Technol, Beijing 100029, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, M ,Cao, XJ ,Mayouma, L ,et al. Trace element characteristics of a Gorham-Stout Syndrome sufferer[J]. CHINESE SCIENCE BULLETIN,2008,53(9):1388-1392. |
APA | Chen, M ,Cao, XJ ,Mayouma, L ,Lu, XF ,Jacques, Y ,&Feng, L .(2008).Trace element characteristics of a Gorham-Stout Syndrome sufferer.CHINESE SCIENCE BULLETIN,53(9),1388-1392. |
MLA | Chen, M ,et al."Trace element characteristics of a Gorham-Stout Syndrome sufferer".CHINESE SCIENCE BULLETIN 53.9(2008):1388-1392. |
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