Symmetry based prostate cancer detection

doi:10.1259/bjr.20150132

CORC > 北京大学 > 工学院

	Symmetry based prostate cancer detection
	Yang, L. ; Xie, Y. ; Li, B. ; Xie, M. ; Wang, X. ; Zhang, J.
刊名	BRITISH JOURNAL OF RADIOLOGY
	2015
关键词	CONTRAST-ENHANCED MRI ADENOCARCINOMA CARCINOMA LOCALIZATION STATISTICS ANTIGEN IMAGES
DOI	10.1259/bjr.20150132
英文摘要	Objective: To retrospectively assess the value of left and right half symmetry analysis in prostate T-2 weighted images (T2WI) for improving prostate cancer (PCa) screening. Methods: T2WI and other data of a total of 66 males were collected; the control group and cancer group had 33 patients each. Thresholding geometric active contours algorithm was used for prostate region segmentation, and the measure of local reflectional symmetry algorithm was applied to extract the longitudinal symmetry axes. After that, cross-correlation coefficients (CCs) of the left and right halves of each prostate were obtained. Results: Data analysis showed that the mean and variance of the value of the left and right half CCs of prostate T2WI in the cancer group and control group were 0.73 +/- 0.05 and 0.82 +/- 0.06, respectively. The area under the receiver operating characteristic curve was 0.87, and the specificity and the sensitivity were 91% and 70%, respectively. The p < 0.001 indicated that the value of CCs of the prostates between the two groups was significantly different. Conclusion: The symmetry in T2WI is a potential useful index for PCa screening and has a potential value for PCa detection and localizations of tumours for biopsy. Advances in knowledge: Texture bilateral symmetry of prostate T2WI is employed to screen the suspected prostate tumour.; SCI(E); ARTICLE; cjr.wangxiaoying@vip.163.com; 1050; 88
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/421123]
专题	工学院
推荐引用方式 GB/T 7714	Yang, L.,Xie, Y.,Li, B.,et al. Symmetry based prostate cancer detection[J]. BRITISH JOURNAL OF RADIOLOGY,2015.
APA	Yang, L.,Xie, Y.,Li, B.,Xie, M.,Wang, X.,&Zhang, J..(2015).Symmetry based prostate cancer detection.BRITISH JOURNAL OF RADIOLOGY.
MLA	Yang, L.,et al."Symmetry based prostate cancer detection".BRITISH JOURNAL OF RADIOLOGY (2015).