Remineralizing Efficacy of Fluorohydroxyapatite Gel on Artificial   Dentinal Caries Lesion

doi:10.1155/2015/380326

CORC > 北京大学 > 工学院

	Remineralizing Efficacy of Fluorohydroxyapatite Gel on Artificial Dentinal Caries Lesion
	Wang, Qianqian ; Liu, Shize ; Gao, Xuejun ; Wei, Yan ; Deng, Xuliang ; Chen, Haifeng ; Zhang, Xuehui
刊名	JOURNAL OF NANOMATERIALS
	2015
关键词	MINERAL TRIOXIDE AGGREGATE CALCIUM-PHOSPHATE IN-VITRO CEMENT HYDROXIDE FLUORIDE GROWTH
DOI	10.1155/2015/380326
英文摘要	The aim was to evaluate the remineralizing efficacy of fluorohydroxyapatite (FHA) gel on artificial dentinal caries lesion in vitro. Artificial carious lesions were made on occlusal cavities of teeth by exposing the dentin surface to a demineralizing solution. Each cavity was capped with a 3mm thick FHA gel for 4 weeks. After the FHA gel was removed, the surface morphology and structure of the dentin were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The dentin mineral density (DMD) was measured by micro-computed tomography (Micro-CT). A layer of dense and orderly hexagonal crystal structure, with average diameter of 1 mu m and thickness of 4 similar to 5 mu m, could be observed on dentin surface. These crystals exhibited elemental peaks for calcium, phosphorus, carbon, and oxygen and characteristic peaks of hydroxyapatite (HA) and fluorapatite (FA) via XRD and FT-IR. The DMD of dentin surface layer significantly increased after it was capped with FHA gel (P < 0.05). In the present study, the FHA gel could rapidly construct apatite on the artificial dentin caries surface and significantly increase the mineral density, which suggests that FHA gel might be a proper IPT material with remineralizing function.; National Basic Research Program of China [2012CB933900]; Key International S&T Cooperation Projects [2011DFA32190]; Key Technologies R&D Program of China [2012BAI07B01]; Science Foundation of Peking University School and Hospital of Stomatology [PKUSS20130103]; SCI(E); EI; ARTICLE; haifeng.chen@pku.edu.cn; zhangxuehui914@163.com; 2015
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/421005]
专题	工学院
推荐引用方式 GB/T 7714	Wang, Qianqian,Liu, Shize,Gao, Xuejun,et al. Remineralizing Efficacy of Fluorohydroxyapatite Gel on Artificial Dentinal Caries Lesion[J]. JOURNAL OF NANOMATERIALS,2015.
APA	Wang, Qianqian.,Liu, Shize.,Gao, Xuejun.,Wei, Yan.,Deng, Xuliang.,...&Zhang, Xuehui.(2015).Remineralizing Efficacy of Fluorohydroxyapatite Gel on Artificial Dentinal Caries Lesion.JOURNAL OF NANOMATERIALS.
MLA	Wang, Qianqian,et al."Remineralizing Efficacy of Fluorohydroxyapatite Gel on Artificial Dentinal Caries Lesion".JOURNAL OF NANOMATERIALS (2015).