QQ客服 官方微博 反馈留言

	Confocal reflectance/auto-fluorescence tomograpy (CRAFT) for early skin cancer diagnosis
	Peng, Tong ; Xie, Hao ; Ding, Yichen ; Wang, Weichao ; Li, Zhiming ; Jin, Dayong ; Tang, Yuanhe ; Ren, Qiushi ; Xi, Peng
	2012
英文摘要	Histopathological analysis has been the gold standard of conventional cancer diagnosis for decades, which is based on the structural and/or biochemical change of the cancerous sites, through biopsy. However, due to cosmetic reasons, the biopsy procedure has to be limited. In this work, we report the noninvasive, in situ, 3-D optical diagnostic method for 'virtual biopsy'. To obtain simultaneously the structural and pathological information, a multimodality Confocal Reflectance/Auto-Fluorescence Tomography (CRAFT) system was established. Nude mice skin with cancerous sites and normal skin sites were compared with the system. The cellular density and reflective intensity in cancerous sites reflects the structural alteration of the tissue. The corresponding NAD(P)H decay index for cancerous sites is 2.45-fold that of normal sites, leading to a clearly separation of the cancerous sites with the healthy control sites. The results are verified by the followed histological analysis. Therefore, CRAFT may provide a novel method for the in vivo, non-invasive diagnosis of early cancer. ? 2012.; EI; 0
语种	英语
内容类型	会议论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/316816]
专题	工学院
推荐引用方式 GB/T 7714	Peng, Tong,Xie, Hao,Ding, Yichen,et al. Confocal reflectance/auto-fluorescence tomograpy (CRAFT) for early skin cancer diagnosis[C]. 见:.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。