Immobilizing natural macromolecule on PLGA electrospun nanofiber with   surface entrapment and entrapment-graft techniques

doi:10.1016/j.colsurfb.2012.01.017

CORC > 北京大学 > 工学院

	Immobilizing natural macromolecule on PLGA electrospun nanofiber with surface entrapment and entrapment-graft techniques
	Meng, Z. X. ; Zeng, Q. T. ; Sun, Z. Z. ; Xu, X. X. ; Wang, Y. S. ; Zheng, W. ; Zheng, Y. F.
刊名	colloids and surfaces b biointerfaces
	2012
关键词	Surface modification Gelatin Sodium alginate PLGA Electrospinning CHONDROCYTES IN-VITRO POLY(L-LACTIC ACID) ENDOTHELIAL-CELLS SCAFFOLDS FABRICATION CHITOSAN COLLAGEN GELATIN BONE DERIVATIVES
DOI	10.1016/j.colsurfb.2012.01.017
英文摘要	Surface entrapment is a convenient method to immobilize the natural macromolecules on the surface of synthetic polymers. In this study, the gelatin modified and sodium alginate/gelatin modified PLGA nanofibrous membranes were fabricated via surface entrapment and entrapment-graft techniques. The surface morphology of the each single modified PLGA nanofiber was as smooth as that of untreated PLGA nanofibers. The results of water angle contact measurements and tensile tests showed that the surface entrapment cannot only improve the hydrophilicity but also enhance mechanical properties of the modified nanofibrous membranes. In addition, the sodium alginate/gelatin modified electrospun PLGA nanofibrous membrane exhibited higher hydrophilicity and better biocompatibility than the simply gelatin modified PLGA nanofibrous membrane, which suggested the surface entrapment is a facile and efficient approach to surface modification for electrospun nanofibours membranes. (C) 2012 Elsevier B.V. All rights reserved.; Biophysics; Chemistry, Physical; Materials Science, Biomaterials; SCI(E); EI; 0; ARTICLE; 44-50; 94
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/233381]
专题	工学院
推荐引用方式 GB/T 7714	Meng, Z. X.,Zeng, Q. T.,Sun, Z. Z.,et al. Immobilizing natural macromolecule on PLGA electrospun nanofiber with surface entrapment and entrapment-graft techniques[J]. colloids and surfaces b biointerfaces,2012.
APA	Meng, Z. X..,Zeng, Q. T..,Sun, Z. Z..,Xu, X. X..,Wang, Y. S..,...&Zheng, Y. F..(2012).Immobilizing natural macromolecule on PLGA electrospun nanofiber with surface entrapment and entrapment-graft techniques.colloids and surfaces b biointerfaces.
MLA	Meng, Z. X.,et al."Immobilizing natural macromolecule on PLGA electrospun nanofiber with surface entrapment and entrapment-graft techniques".colloids and surfaces b biointerfaces (2012).