A study on small-world brain functional networks altered by postherpetic   neuralgia

doi:10.1016/j.mri.2013.12.016

CORC > 北京大学 > 工学院

	A study on small-world brain functional networks altered by postherpetic neuralgia
	Zhang, Yue ; Liu, Jing ; Li, Longchuan ; Du, Minyi ; Fang, Wenxue ; Wang, Dongxin ; Jiang, Xuexiang ; Hu, Xiaoping ; Zhang, Jue ; Wang, Xiaoying ; Fang, Jing
刊名	磁共振成像
	2014
关键词	Small-world Brain functional networks Resting-state fMRI Chronic pain Postherpetic neuralgia AFFECTIVE DIMENSION CHRONIC PAIN PERCEPTION MODULATION MECHANISMS DYNAMICS
DOI	10.1016/j.mri.2013.12.016
英文摘要	Understanding the effect of postherpetic neuralgia (PHN) pain on brain activity is important for clinical strategies. This is the first study, to our knowledge, to relate PHN pain to small-world properties of brain functional networks. Functional magnetic resonance imaging (fMRI) was used to construct functional brain networks of the subjects during the resting state. Sixteen patients with PHN pain and 16 (8 males, 8 females for both groups) age-matched controls were studied. The PHN patients exhibited decreased local efficiency along with non-significant changes of global efficiency in comparison with the healthy controls. Moreover, regional nodal efficiency was found to be significantly affected by PHN pain in the areas related to sense (postcentral gyrus, inferior parietal gyrus and thalamus), memory/affective processes (parahippocampal gyms) and emotional activities (putamen). Significant correlation (p <0.05) was also found between the nodal efficiency of putamen and pain intensity in PHN patients. Our results suggest that PHN modulates the local efficiency, and the small-world properties of brain networks may have potentials to objectively evaluate pain information in clinic. (C) 2014 Elsevier Inc. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000333868200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Radiology, Nuclear Medicine & Medical Imaging; SCI(E); PubMed; 4; ARTICLE; zhangjue@pku.edu.cn; cjr.wangxiaoying@vip.163.com; 4; 359-365; 32
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/153897]
专题	工学院
推荐引用方式 GB/T 7714	Zhang, Yue,Liu, Jing,Li, Longchuan,et al. A study on small-world brain functional networks altered by postherpetic neuralgia[J]. 磁共振成像,2014.
APA	Zhang, Yue.,Liu, Jing.,Li, Longchuan.,Du, Minyi.,Fang, Wenxue.,...&Fang, Jing.(2014).A study on small-world brain functional networks altered by postherpetic neuralgia.磁共振成像.
MLA	Zhang, Yue,et al."A study on small-world brain functional networks altered by postherpetic neuralgia".磁共振成像 (2014).