Aptamer-Binding Directed DNA Origami Pattern for Logic Gates

doi:10.1021/acsami.6b10266

CORC > 北京大学 > 信息科学技术学院

	Aptamer-Binding Directed DNA Origami Pattern for Logic Gates
	Yang, Jing ; Jiang, Shuoxing ; Liu, Xiangrong ; Pan, Linqiang ; Zhang, Cheng
刊名	ACS APPLIED MATERIALS & INTERFACES
	2016
关键词	DNA origami aptamer DNAzyme tile filling logic gate SINGLE-MOLECULE VISUALIZATION DOUBLE-CROSSOVER MOLECULES CONDUCTIVE NANOWIRES DNAZYME CRYSTALS NANOFABRICATION NANOSTRUCTURE OCTAHEDRON NANOTUBES POLYHEDRA
DOI	10.1021/acsami.6b10266
英文摘要	In this study, an aptamer-substrate strategy is introduced to control programmable DNA origami pattern. Combined with DNA aptamer-substrate binding and DNAzyme-cutting, small DNA tiles were specifically controlled to fill into the predesigned DNA origami frame. Here, a set of DNA logic gates (OR, YES, and AND) are performed in response to the stimuli of adenosine triphosphate (ATP) and cocaine. The experimental results are confirmed by AFM imaging and time dependent fluorescence changes, demonstrating that the geometric patterns are regulated in a controllable and programmable manner. Our approach provides a new platform for engineering programmable origami nanopatterns and constructing complex DNA nanodevices.; National Natural Science Foundation of China [61370099, 61272161, 61425002, 61472333, 61572046, 61320106005]; SCI(E); ARTICLE; lqpan@mail.hust.edu.cn; zhangcheng369@pku.edu.cn; 49; 34054-34060; 8
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/458053]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Yang, Jing,Jiang, Shuoxing,Liu, Xiangrong,et al. Aptamer-Binding Directed DNA Origami Pattern for Logic Gates[J]. ACS APPLIED MATERIALS & INTERFACES,2016.
APA	Yang, Jing,Jiang, Shuoxing,Liu, Xiangrong,Pan, Linqiang,&Zhang, Cheng.(2016).Aptamer-Binding Directed DNA Origami Pattern for Logic Gates.ACS APPLIED MATERIALS & INTERFACES.
MLA	Yang, Jing,et al."Aptamer-Binding Directed DNA Origami Pattern for Logic Gates".ACS APPLIED MATERIALS & INTERFACES (2016).