Continuous flowing micro-reactor for aqueous reaction at temperature   higher than 100 degrees C

doi:10.1063/1.4807463

CORC > 北京大学 > 信息科学技术学院

	Continuous flowing micro-reactor for aqueous reaction at temperature higher than 100 degrees C
	Xie, Fei ; Wang, Baojun ; Wang, Wei ; Dong, Tian ; Tong, Jianhua ; Xia, Shanhong ; Wu, Wengang ; Li, Zhihong
刊名	biomicrofluidics
	2013
关键词	INDUCED DIGESTION HIGH-PRESSURE MICROFLUIDICS PHOSPHORUS CHIP CHEMISTRY PRODUCTS WATERS
DOI	10.1063/1.4807463
英文摘要	Some aqueous reactions in biological or chemical fields are accomplished at a high temperature. When the reaction temperature is higher than 100 degrees C, an autoclave reactor is usually required to elevate the boiling point of the water by creating a high-pressure environment in a closed system. This work presented an alternative continuous flowing microfluidic solution for aqueous reaction with a reaction temperature higher than 100 degrees C. The pressure regulating function was successfully fulfilled by a small microchannel based on a delicate hydrodynamic design. Combined with micro heater and temperature sensor that integrated in a single chip by utilizing silicon-based microfabrication techniques, this pressure regulating microchannel generated a high-pressure/high-temperature environment in the upstream reaction zone when the reagents continuously flow through the chip. As a preliminary demonstration, thermal digestion of aqueous total phosphorus sample was achieved in this continuous flowing micro-reactor at a working pressure of 990 kPa (under the working flow rate of 20 nl/s) along with a reaction temperature of 145 degrees C. This continuous flowing microfluidic solution for high-temperature reaction may find applications in various micro total analysis systems. (C) 2013 AIP Publishing LLC.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000321145800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemical Research Methods; Biophysics; Nanoscience & Nanotechnology; Physics, Fluids & Plasmas; SCI(E); EI; PubMed; 2; ARTICLE; 3; 34104; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/151795]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Xie, Fei,Wang, Baojun,Wang, Wei,et al. Continuous flowing micro-reactor for aqueous reaction at temperature higher than 100 degrees C[J]. biomicrofluidics,2013.
APA	Xie, Fei.,Wang, Baojun.,Wang, Wei.,Dong, Tian.,Tong, Jianhua.,...&Li, Zhihong.(2013).Continuous flowing micro-reactor for aqueous reaction at temperature higher than 100 degrees C.biomicrofluidics.
MLA	Xie, Fei,et al."Continuous flowing micro-reactor for aqueous reaction at temperature higher than 100 degrees C".biomicrofluidics (2013).