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	Transcriptional responses of earthworm (Eisenia fetida) exposed to naphthenic acids in soil
	Wang, Jie ; Cao, Xiaofeng ; Sun, Jinhua ; Chai, Liwei ; Huang, Yi ; Tang, Xiaoyan
刊名	environmental pollution
	2015
DOI	10.1016/j.envpol.2015.05.006
英文摘要	In this study, earthworms (Eisenia fetida) were exposed to commercial NAs contaminated soil, and changes in the levels of reactive oxygen species (ROS) and gene expressions of their defense system were monitored. The effects on the gene expression involved in reproduction and carcinogenesis were also evaluated. Significant increases in ROS levels was observed in NAs exposure groups, and the superoxide dismutase (SOD) and catalase (CAT) genes were both up-regulated at low and medium exposure doses, which implied NAs might exert toxicity by oxidative stress. The transcription of CRT and HSP70 coincided with oxidative stress, which implied both chaperones perform important functions in the protection against oxidative toxicity. The upregulation of TCTP gene indicated a potential adverse effect of NAs to terrestrial organisms through induction of carcinogenesis, and the downregulation of ANN gene indicated that NAs might potentially result in deleterious reproduction effects. ? 2015 Elsevier Ltd. All rights reserved.; SCI(E); EI; PubMed; 0; ARTICLE; yhuang@pku.edu.cn; 264-270; 204
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/263534]
专题	环境科学与工程学院
推荐引用方式 GB/T 7714	Wang, Jie,Cao, Xiaofeng,Sun, Jinhua,et al. Transcriptional responses of earthworm (Eisenia fetida) exposed to naphthenic acids in soil[J]. environmental pollution,2015.
APA	Wang, Jie,Cao, Xiaofeng,Sun, Jinhua,Chai, Liwei,Huang, Yi,&Tang, Xiaoyan.(2015).Transcriptional responses of earthworm (Eisenia fetida) exposed to naphthenic acids in soil.environmental pollution.
MLA	Wang, Jie,et al."Transcriptional responses of earthworm (Eisenia fetida) exposed to naphthenic acids in soil".environmental pollution (2015).

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