CORC  > 北京大学  > 心理与认知科学学院
Visual search in Alzheimer's disease - fMRI study
Hao, J ; Li, KC ; Li, K ; Zhang, DX ; Wang, W ; Yan, B ; Yang, YH ; Wang, Y ; Chen, Q ; Shan, BC ; Zhou, XL
2004
关键词SELECTIVE ATTENTION SPATIAL ATTENTION DIVIDED ATTENTION CONJUNCTION ACTIVATION DEMENTIA PATTERNS TASK PET
英文摘要The aim was to investigate the neural basis of visual attention deficits in Alzheimer's disease (AD) patients using functional MRI. Thirteen AD patients and 13 age-matched controls participated in the experiment of two visual search tasks, one was a pop-out task, the other was a conjunction task. The fMRI data were collected on a 1-5T MRI system and analyzed by SPM99. Both groups revealed almost the same networks engaged in both tasks, including the superior parietal lobule (SPL), frontal and occipito-temporal cortical regions (OTC), primary visual cortex and some subcortical structures. AD patients have a particular impairment in the conjunction task. The most pronounced differences were more activity in the SPL in controls and more activity in the OTC in AD patients. These results imply that the mechanisms controlling spatial shifts of attention axe impaired in AD patients.; Computer Science, Interdisciplinary Applications; Computer Science, Theory & Methods; Radiology, Nuclear Medicine & Medical Imaging; SCI(E); CPCI-S(ISTP); 1
语种英语
内容类型其他
源URL[http://ir.pku.edu.cn/handle/20.500.11897/400524]  
专题心理与认知科学学院
推荐引用方式
GB/T 7714
Hao, J,Li, KC,Li, K,et al. Visual search in Alzheimer's disease - fMRI study. 2004-01-01.
个性服务
查看访问统计
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。


©版权所有 ©2017 CSpace - Powered by CSpace