An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness | |
Lee, Tatia M. C. ; Chan, Chetwyn C. H. ; Han, Shi-hui ; Leung, Ada W. S. ; Fox, Peter T. ; Gao, Jia-Hong | |
刊名 | 神经科学快报
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2008 | |
关键词 | orbitofrontal cortex insula anterior cingulate cortex dorsolateral prefrontal cortex risk taking parietal cortex DECISION-MAKING ORBITOFRONTAL CORTEX PREFRONTAL CORTEX NEURAL BASIS ANTERIOR CINGULATE FUNCTIONAL MRI ACTIVATION ANTICIPATION UNCERTAINTY INHIBITION |
DOI | 10.1016/j.neulet.2008.04.061 |
英文摘要 | This event-related functional Magnetic Resonance Imaging study examined the differential neural activities associated with a Risky-Gains task in 18 healthy individuals of high (n = 9) or low (n = 9) impulsiveness, according to their scores on the Barratt Impulsiveness Scale (BIS). The neural activities of people belonging to the high and low impulsiveness groups were monitored by a 3T MRI scanner while they were performing the Risky-Gains task. We demonstrated that a stronger activation in the insula-orbitofrontal-parietal regions was found in the high impulsiveness group compared to the low impulsiveness group. However, the levels of activation in the lateral prefrontal and anterior cingulate regions did not differ between the two groups. The findings suggest that the neural substrates of comprehension of cognitive and affective information associated with risk-taking decision making may vary according to the impulsiveness among healthy individuals. (C) 2008 Elsevier Ireland Ltd. All rights reserved.; Neurosciences; SCI(E); 14; ARTICLE; 2; 138-141; 438 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/248879] ![]() |
专题 | 心理与认知科学学院 |
推荐引用方式 GB/T 7714 | Lee, Tatia M. C.,Chan, Chetwyn C. H.,Han, Shi-hui,et al. An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness[J]. 神经科学快报,2008. |
APA | Lee, Tatia M. C.,Chan, Chetwyn C. H.,Han, Shi-hui,Leung, Ada W. S.,Fox, Peter T.,&Gao, Jia-Hong.(2008).An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness.神经科学快报. |
MLA | Lee, Tatia M. C.,et al."An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness".神经科学快报 (2008). |
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