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	DNA replication initiator Cdc6 also regulates initiation of ribosomal DNA transcription in human cells; DNA replication initiator Cdc6 also regulates initiation of ribosomal DNA transcription in human cells
	Shijiao Huang ; Xiaowei Xu ; Guopeng Wang ; Wenbing Xie ; Wei Tao ; Qing Jiang ; Chuanmao Zhang
	2015
关键词	replication DNA initiator ribosomal promoter upstream initiation eukaryotic RNA initiating replication DNA initiator ribosomal promoter upstream initiation eukaryotic RNA initiating
英文摘要	Cdc6 is a crucial component of the pre-replication complex(pre-RC) in metazoan cells that initiates and regulates DNA replication.By proteomic analysis,we identified that Cdc6 also interacts with Pol Ⅰ(RNA polymerase Ⅰ)and its co-factors,and promotes the rDNA transcription in G1 phase.Pol; Cdc6 is a crucial component of the pre-replication complex(pre-RC) in metazoan cells that initiates and regulates DNA replication.By proteomic analysis,we identified that Cdc6 also interacts with Pol Ⅰ(RNA polymerase Ⅰ)and its co-factors,and promotes the rDNA transcription in G1 phase.Pol; 中国生物物理学会、中国科学院生物物理研究所; 1
语种	英语
出处	第十四次中国暨国际生物物理大会（ICBC2015）
内容类型	其他
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/480061]
专题	生命科学学院
推荐引用方式 GB/T 7714	Shijiao Huang,Xiaowei Xu,Guopeng Wang,et al. DNA replication initiator Cdc6 also regulates initiation of ribosomal DNA transcription in human cells, DNA replication initiator Cdc6 also regulates initiation of ribosomal DNA transcription in human cells. 2015-01-01.

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