Light-Dependent Degradation of PIF3 by SCFEBF1/2 Promotes a   Photomorphogenic Response in Arabidopsis

doi:10.1016/j.cub.2017.06.062

CORC > 北京大学 > 生命科学学院

	Light-Dependent Degradation of PIF3 by SCFEBF1/2 Promotes a Photomorphogenic Response in Arabidopsis
	Dong, Jie ; Ni, Weimin ; Yu, Renbo ; Deng, Xing Wang ; Chen, Haodong ; Wei, Ning
刊名	CURRENT BIOLOGY
	2017
关键词	PHYTOCHROME INTERACTING FACTOR-3 TRANSCRIPTION FACTOR PIF3 F-BOX PROTEINS SIGNAL-TRANSDUCTION UBIQUITIN LIGASES ETHYLENE GAS PHOSPHORYLATION PHOTORECEPTORS ETHYLENE-INSENSITIVE3 MECHANISM
DOI	10.1016/j.cub.2017.06.062
英文摘要	Plant seedlings emerging from darkness into the light environment undergo photomorphogenesis, which enables autotrophic growth with optimized morphology and physiology. During this transition, plants must rapidly remove photomorphogenic repressors accumulated in the dark. Among them is PHYTOCHROME-INTERACTING FACTOR 3 (PIF3), a key transcription factor promoting hypocotyl growth. Here we report that, in response to light activation of phytochrome photoreceptors, EIN3-BINDING F BOX PROTEINs (EBFs) 1 and 2 mediate PIF3 protein degradation in a manner dependent on light-induced phosphorylation of PIF3. Whereas PIF3 binds EBFs independent of light, the recruitment of PIF3-EBFs to the core SKP1-CUL1-F box protein (SCF) scaffold is facilitated by light signals or PIF3 phosphorylation. We also found that previously identified LIGHT-RESPONSE BRIC-A-BRACK/TRAMTRACK/BROAD (LRB) E3 ubiquitin ligases target phytochrome B (phyB) and PIF3 primarily under high-light conditions, whereas EBF1/2 vigorously target PIF3 degradation under wide ranges of light intensity without affecting the abundance of phyB. Both genetic and molecular data support that SCFEBF1/2 function as photomorphogenic E3s during seedling development.; National Natural Science Foundation of China [31621001, 31271294, 31330048]; NIH of the United States [R01GM047850]; National Key Research and Development Program of China [2017YFA0503801]; Peking-Tsinghua Center for Life Sciences; State Key Laboratory of Protein and Plant Gene Research; SCI(E); ARTICLE; 16; 2420-+; 27
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/471406]
专题	生命科学学院
推荐引用方式 GB/T 7714	Dong, Jie,Ni, Weimin,Yu, Renbo,et al. Light-Dependent Degradation of PIF3 by SCFEBF1/2 Promotes a Photomorphogenic Response in Arabidopsis[J]. CURRENT BIOLOGY,2017.
APA	Dong, Jie,Ni, Weimin,Yu, Renbo,Deng, Xing Wang,Chen, Haodong,&Wei, Ning.(2017).Light-Dependent Degradation of PIF3 by SCFEBF1/2 Promotes a Photomorphogenic Response in Arabidopsis.CURRENT BIOLOGY.
MLA	Dong, Jie,et al."Light-Dependent Degradation of PIF3 by SCFEBF1/2 Promotes a Photomorphogenic Response in Arabidopsis".CURRENT BIOLOGY (2017).