Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment

doi:10.18632/oncotarget.8206

CORC > 北京大学 > 生命科学学院

	Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment
	Li, Jing ; Yang, Zuozhang ; Li, Yi ; Xia, Junfeng ; Li, Dongqi ; Li, Huiling ; Ren, Mingyan ; Liao, Yedan ; Yu, Shunling ; Chen, Yanjin ; Yang, Yihao ; Zhang, Ya
刊名	ONCOTARGET
	2016
关键词	apoptosis autophagy necroptosis chemotherapy resistance osteosarcoma CELASTROL INDUCES APOPTOSIS TRAIL-INDUCED APOPTOSIS PROTEIN-KINASE 1 IN-VITRO SIGNALING PATHWAY LUNG METASTASIS HMGB1-MEDIATED AUTOPHAGY INHIBITS PROLIFERATION MITOCHONDRIAL PATHWAY PROTEASOME INHIBITOR
DOI	10.18632/oncotarget.8206
英文摘要	Osteosarcoma is the most common primary bone tumor in children and adolescents. Although combined therapy including surgery and multi-agent chemotherapy have resulted in great improvements in the overall survival of patients, chemoresistance remains an obstacle for the treatment of osteosarcoma. Molecular targets or effective agents that are actively involved in cell death including apoptosis, autophagy and necroptosis have been studied. We summarized how these agents (novel compounds, miRNAs, or proteins) regulate apoptotic, autophagic and necroptotic pathways; and discussed the current knowledge on the role of these new agents in chemotherapy resistance in osteosarcoma.; National Natural Science Foundation of China [31300624]; China Postdoctoral Science Foundation [2013M530473]; SCI(E); REVIEW; yangzuozhang@163.com; 28; 44763-44778; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/458973]
专题	生命科学学院
推荐引用方式 GB/T 7714	Li, Jing,Yang, Zuozhang,Li, Yi,et al. Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment[J]. ONCOTARGET,2016.
APA	Li, Jing.,Yang, Zuozhang.,Li, Yi.,Xia, Junfeng.,Li, Dongqi.,...&Zhang, Ya.(2016).Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment.ONCOTARGET.
MLA	Li, Jing,et al."Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment".ONCOTARGET (2016).