CPVT-related mutation increased RyR2 channel sensitivity to calcium influx through L-type calcium channels; CPVT-related mutation increased RyR2 channel sensitivity to calcium influx through L-type calcium channels | |
Yun-Bo Guo ; Hua-Qian Yang ; Jing-Chao Li ; Shi-Qiang Wang | |
2012 | |
关键词 | CPVT RyR2 R2474S calcium CPVT RyR2 R2474S calcium |
英文摘要 | Catecholaminergic polymorphic ventricular tachycardia(CPVT) is an arrhythmogenic cardiomyopathy that manifests as recurrent syncope and sudden cardiac death triggered by high adrenergic tone.Mutations in the cardiac ryanodine receptor(RyR2) are known to be the predominant genetic causes of CPVT.H...; Catecholaminergic polymorphic ventricular tachycardia(CPVT) is an arrhythmogenic cardiomyopathy that manifests as recurrent syncope and sudden cardiac death triggered by high adrenergic tone.Mutations in the cardiac ryanodine receptor(RyR2) are known to be the predominant genetic causes of CPVT.H...; 中国科学院上海生命科学研究院(Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences)、中国生理学会(Chinese Association for Physiolog; 1; VOL.64 |
语种 | 英语 |
出处 | 2012国际生理学学术大会 |
内容类型 | 其他 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/449015] |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Yun-Bo Guo,Hua-Qian Yang,Jing-Chao Li,et al. CPVT-related mutation increased RyR2 channel sensitivity to calcium influx through L-type calcium channels, CPVT-related mutation increased RyR2 channel sensitivity to calcium influx through L-type calcium channels. 2012-01-01. |
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