Horizontal gene transfer in an acid mine drainage microbial community

doi:10.1186/s12864-015-1720-0

CORC > 北京大学 > 生命科学学院

	Horizontal gene transfer in an acid mine drainage microbial community
	Guo, Jiangtao ; Wang, Qi ; Wang, Xiaoqi ; Wang, Fumeng ; Yao, Jinxian ; Zhu, Huaiqiu
刊名	BMC GENOMICS
	2015
关键词	Environmental microbes Metagenome Microevolution Computational identification PHYLOGENETIC TREE SELECTION ESCHERICHIA-COLI MAXIMUM-LIKELIHOOD RIBOSOMAL-RNA DECARBOXYLASE SYSTEM EVOLUTION RESISTANCE PROTEIN BACTERIA GENOMES
DOI	10.1186/s12864-015-1720-0
英文摘要	Background: Horizontal gene transfer (HGT) has been widely identified in complete prokaryotic genomes. However, the roles of HGT among members of a microbial community and in evolution remain largely unknown. With the emergence of metagenomics, it is nontrivial to investigate such horizontal flow of genetic materials among members in a microbial community from the natural environment. Because of the lack of suitable methods for metagenomics gene transfer detection, microorganisms from a low-complexity community acid mine drainage (AMD) with near-complete genomes were used to detect possible gene transfer events and suggest the biological significance. Results: Using the annotation of coding regions by the current tools, a phylogenetic approach, and an approximately unbiased test, we found that HGTs in AMD organisms are not rare, and we predicted 119 putative transferred genes. Among them, 14 HGT events were determined to be transfer events among the AMD members. Further analysis of the 14 transferred genes revealed that the HGT events affected the functional evolution of archaea or bacteria in AMD, and it probably shaped the community structure, such as the dominance of G-plasma in archaea in AMD through HGT. Conclusions: Our study provides a novel insight into HGT events among microorganisms in natural communities. The interconnectedness between HGT and community evolution is essential to understand microbial community formation and development.; National "Twelfth Five-Year" Plan for Science & Technology of China [2012BAI06B02]; National Natural Science Foundation of China [91231119]; National Basic Research Program of China [2011CB707500]; SCI(E); PubMed; ARTICLE; hqzhu@pku.edu.cn; 496; 16
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/418604]
专题	生命科学学院工学院
推荐引用方式 GB/T 7714	Guo, Jiangtao,Wang, Qi,Wang, Xiaoqi,et al. Horizontal gene transfer in an acid mine drainage microbial community[J]. BMC GENOMICS,2015.
APA	Guo, Jiangtao,Wang, Qi,Wang, Xiaoqi,Wang, Fumeng,Yao, Jinxian,&Zhu, Huaiqiu.(2015).Horizontal gene transfer in an acid mine drainage microbial community.BMC GENOMICS.
MLA	Guo, Jiangtao,et al."Horizontal gene transfer in an acid mine drainage microbial community".BMC GENOMICS (2015).