CyanOmics: an integrated database of omics for the model cyanobacterium   Synechococcus sp PCC 7002

doi:10.1093/database/bau127

CORC > 北京大学 > 生命科学学院

	CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp PCC 7002
	Yang, Yaohua ; Feng, Jie ; Li, Tao ; Ge, Feng ; Zhao, Jindong
刊名	database the journal of biological databases and curation
	2015
关键词	OXIDATIVE STRESS SP PCC-7002 HIGH-LIGHT GENOME GENERATION SEQUENCE GROWTH MUTANT ROLES
DOI	10.1093/database/bau127
英文摘要	Cyanobacteria are an important group of organisms that carry out oxygenic photosynthesis and play vital roles in both the carbon and nitrogen cycles of the Earth. The annotated genome of Synechococcus sp. PCC 7002, as an ideal model cyanobacterium, is available. A series of transcriptomic and proteomic studies of Synechococcus sp. PCC 7002 cells grown under different conditions have been reported. However, no database of such integrated omics studies has been constructed. Here we present CyanOmics, a database based on the results of Synechococcus sp. PCC 7002 omics studies. CyanOmics comprises one genomic dataset, 29 transcriptomic datasets and one proteomic dataset and should prove useful for systematic and comprehensive analysis of all those data. Powerful browsing and searching tools are integrated to help users directly access information of interest with enhanced visualization of the analytical results. Furthermore, Blast is included for sequence-based similarity searching and Cluster 3.0, as well as the R hclust function is provided for cluster analyses, to increase CyanOmics's usefulness. To the best of our knowledge, it is the first integrated omics analysis database for cyanobacteria. This database should further understanding of the transcriptional patterns, and proteomic profiling of Synechococcus sp. PCC 7002 and other cyanobacteria. Additionally, the entire database framework is applicable to any sequenced prokaryotic genome and could be applied to other integrated omics analysis projects.; Mathematical & Computational Biology; SCI(E); 0; ARTICLE; litao@ihb.ac.cn; gefeng@ihb.ac.cn
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/386037]
专题	生命科学学院
推荐引用方式 GB/T 7714	Yang, Yaohua,Feng, Jie,Li, Tao,et al. CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp PCC 7002[J]. database the journal of biological databases and curation,2015.
APA	Yang, Yaohua,Feng, Jie,Li, Tao,Ge, Feng,&Zhao, Jindong.(2015).CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp PCC 7002.database the journal of biological databases and curation.
MLA	Yang, Yaohua,et al."CyanOmics: an integrated database of omics for the model cyanobacterium Synechococcus sp PCC 7002".database the journal of biological databases and curation (2015).