Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy

CORC > 北京大学 > 生命科学学院

	Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy
	Sun J R ; Yu R Y ; Liu W S ; Wang Y F
刊名	sheng li xue bao acta physiologica sinica
	1998
英文摘要	Vestibular compensation is the most extensively investigated model for neuroplasticity. Growth-associated protein (GAP-43) mRNA plays a significant role in nerve regeneration and synaptic remodeling. Using in situ hybridization with DIG (digoxigenin)-labeled GAP-43 cDNA probe, changes of GAP-43 mRNA expression in the medial vestibular nucleus in the labyrinthectomized rats at 5, 12, 20 and 30th day after operation were investigated. The results clearly demonstrated that labyrinthectomy increased GAP-43 mRNA expression to different extents and amplitudes in bilateral medial vestibular nuclei. This finding suggests that upregulation of GAP-43 mRNA expression is related to regenerative sprouting, synaptic remodeling and neuroplasticity in vestibular compensation.; PubMed; 0; 5; 587-90; 50
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/347463]
专题	生命科学学院
推荐引用方式 GB/T 7714	Sun J R,Yu R Y,Liu W S,et al. Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy[J]. sheng li xue bao acta physiologica sinica,1998.
APA	Sun J R,Yu R Y,Liu W S,&Wang Y F.(1998).Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy.sheng li xue bao acta physiologica sinica.
MLA	Sun J R,et al."Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy".sheng li xue bao acta physiologica sinica (1998).