Safety assessment for genetically modified sweet pepper and tomato

doi:10.1016/S0300-483X(03)00111-2

CORC > 北京大学 > 生命科学学院

	Safety assessment for genetically modified sweet pepper and tomato
	Chen, ZL ; Gu, HY ; Li, Y ; Su, YL ; Wu, P ; Jiang, ZC ; Ming, XT ; Tian, JH ; Pan, NS ; Qu, LJ
刊名	toxicology
	2003
关键词	GM plants safety assessment CMV-cp feeding test TRANSGENIC PLANTS SOYBEANS PROTEIN
DOI	10.1016/S0300-483X(03)00111-2
英文摘要	The coat protein (CP) gene of cucumber mosaic virus (CMV) was cloned from a Chinese CMV isolate, the CaMV promoter and NOS terminator added and the gene construct was transformed into both sweet pepper and tomato plants to confer resistance to CMV. Safety assessments of these genetically modified (GM) plants were conducted. It was found that these two GM products showed no genotoxicity either in vitro or in vivo by the micronucleus test, sperm aberration test and Ames test. Animal feeding studies showed no significant differences in growth, body weight gain, food consumption, hematology, blood biochemical indices, organ weights and histopathology between rats or mice of either sex fed with either GM sweet pepper or tomato diets compared with those with non-GM diets. These results demonstrate that the CMV-resistant sweet pepper and tomato are comparable to the non-GM counterparts in terms of food safety. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.; Pharmacology & Pharmacy; Toxicology; SCI(E); PubMed; 25; ARTICLE; 2-3; 297-307; 188
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/200091]
专题	生命科学学院
推荐引用方式 GB/T 7714	Chen, ZL,Gu, HY,Li, Y,et al. Safety assessment for genetically modified sweet pepper and tomato[J]. toxicology,2003.
APA	Chen, ZL.,Gu, HY.,Li, Y.,Su, YL.,Wu, P.,...&Qu, LJ.(2003).Safety assessment for genetically modified sweet pepper and tomato.toxicology.
MLA	Chen, ZL,et al."Safety assessment for genetically modified sweet pepper and tomato".toxicology (2003).