Post-synthetic modification of an amino-functionalized metal-organic   framework for highly efficient enrichment of N-linked glycopeptides

doi:10.1039/c6nr02490d

CORC > 北京大学 > 化学与分子工程学院

	Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides
	Ma, Wen ; Xu, Linnan ; Li, Ze ; Sun, Yunlong ; Bai, Yu ; Liu, Huwei
刊名	NANOSCALE
	2016
关键词	CHROMATOGRAPHIC-SEPARATION SELECTIVE ENRICHMENT MASS-SPECTROMETRY MAGNETIC NANOPARTICLES GLYCOPROTEINS GLYCOSYLATION MIL-101(CR) ADSORPTION CHEMISTRY CAPTURE
DOI	10.1039/c6nr02490d
英文摘要	A maltose-functionalized metal-organic framework (MOF), MIL-101(Cr)-maltose, was developed via a simple two step post-synthetic modification of MIL-101(Cr)-NH2. With the use of this nanomaterial, 33 glycopeptides were detected from the digest of human immunoglobulin G, demonstrating its high efficiency in glycoproteomic analysis. More importantly, the generic functionalization route from amino-derived MOFs opens a new perspective in material design in sample preparation.; National Natural Science Foundation of China [21322505, 21575007, 21527809]; Ministry of Science and Technology of China [2012YQ09019409]; SCI(E); EI; ARTICLE; yu.bai@pku.edu.cn; 21; 10908-10912; 8
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/437143]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Ma, Wen,Xu, Linnan,Li, Ze,et al. Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides[J]. NANOSCALE,2016.
APA	Ma, Wen,Xu, Linnan,Li, Ze,Sun, Yunlong,Bai, Yu,&Liu, Huwei.(2016).Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides.NANOSCALE.
MLA	Ma, Wen,et al."Post-synthetic modification of an amino-functionalized metal-organic framework for highly efficient enrichment of N-linked glycopeptides".NANOSCALE (2016).