Non-equilibrium behaviour in coacervate-based protocells under   electric-field-induced excitation

doi:10.1038/ncomms10658

CORC > 北京大学 > 化学与分子工程学院

	Non-equilibrium behaviour in coacervate-based protocells under electric-field-induced excitation
	Yin, Yudan ; Niu, Lin ; Zhu, Xiaocui ; Zhao, Meiping ; Zhang, Zexin ; Mann, Stephen ; Liang, Dehai
刊名	NATURE COMMUNICATIONS
	2016
关键词	MEMBRANE MICRODROPLETS DROPLETS COMPLEX COMPARTMENTALIZATION COLLOIDOSOMES CURRENTS SYSTEMS ROUTE MODEL
DOI	10.1038/ncomms10658
英文摘要	Although numerous strategies are now available to generate rudimentary forms of synthetic cell-like entities, minimal progress has been made in the sustained excitation of artificial protocells under non-equilibrium conditions. Here we demonstrate that the electric field energization of coacervate microdroplets comprising polylysine and short single strands of DNA generates membrane-free protocells with complex, dynamical behaviours. By confining the droplets within a microfluidic channel and applying a range of electric field strengths, we produce protocells that exhibit repetitive cycles of vacuolarization, dynamical fluctuations in size and shape, chaotic growth and fusion, spontaneous ejection and sequestration of matter, directional capture of solute molecules, and pulsed enhancement of enzyme cascade reactions. Our results highlight new opportunities for the study of non-equilibrium phenomena in synthetic protocells, provide a strategy for inducing complex behaviour in electrostatically assembled soft matter microsystems and illustrate how dynamical properties can be activated and sustained in microcompartmentalized media.; SCI(E); PubMed; ARTICLE; s.mann@bristol.ac.uk; dliang@pku.edu.cn; 10658; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/434939]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Yin, Yudan,Niu, Lin,Zhu, Xiaocui,et al. Non-equilibrium behaviour in coacervate-based protocells under electric-field-induced excitation[J]. NATURE COMMUNICATIONS,2016.
APA	Yin, Yudan.,Niu, Lin.,Zhu, Xiaocui.,Zhao, Meiping.,Zhang, Zexin.,...&Liang, Dehai.(2016).Non-equilibrium behaviour in coacervate-based protocells under electric-field-induced excitation.NATURE COMMUNICATIONS.
MLA	Yin, Yudan,et al."Non-equilibrium behaviour in coacervate-based protocells under electric-field-induced excitation".NATURE COMMUNICATIONS (2016).