利用UPLC-MS/MS方法定量人血浆中紫杉醇药物总量及游离紫杉醇的浓度 | |
简南城 ; 郑昕 ; 张一鸣 ; 江骥 ; 张新祥 | |
2014 | |
关键词 | Paclitaxel UPLC-MS/MS |
英文摘要 | To establish the total amount detected in human plasma paclitaxel HPLC-tandem mass spectrometry.Liquid-liquid extraction method for processing plasma samples were determined using Waters ACQUITY UPLC BEH column (2.1 × 50 mm, 1.7 μm) of the sample and the internal standard are separated to 2 mmol/L aqueous ammonium acetate and 0.1% FA methanol as the mobile phase by electrospray ionization (ESI), the positive ion scan, m μLtiple reaction monitoring (MRM) mass spectra were measured scanning.; 45-47 |
语种 | 中文 |
出处 | 2014年全国有机质谱学术会议 |
内容类型 | 其他 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/422494] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | 简南城,郑昕,张一鸣,等. 利用UPLC-MS/MS方法定量人血浆中紫杉醇药物总量及游离紫杉醇的浓度. 2014-01-01. |
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