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Magnetic forces produced by rectangular permanent magnets in static microsystems
Gassner, Anne-Laure ; Abonnenc, Melanie ; Chen, Hong-Xu ; Morandini, Jacques ; Josserand, Jacques ; Rossier, Joel S. ; Busnel, Jean-Marc ; Girault, Hubert H.
刊名芯片实验室
2009
关键词ON-COLUMN CAPTURE MICROFLUIDIC CHANNEL SEPARATION BEADS PARTICLES SYSTEMS PROTEIN CHIP FLOW ELECTROMAGNETS
DOI10.1039/b901865d
英文摘要Finite element numerical simulations were carried out in 2D geometries to map the magnetic field and force distribution produced by rectangular permanent magnets as a function of their size and position with respect to a microchannel. A single magnet, two magnets placed in attraction and in repulsion have been considered. The goal of this work is to show where magnetic beads are preferentially captured in a microchannel. These simulations were qualitatively corroborated, in one geometrical case, by microscopic visualizations of magnetic bead plug formation in a capillary. The results show that the number of plugs is configuration dependent with: in attraction, one plug in the middle of the magnets; in repulsion, two plugs near the edges of the magnets; and with a single magnet, a plug close to the center of the magnet. The geometry of the magnets (h and l are the height and length of the magnets respectively) and their relative spacing s has a significant impact on the magnetic flux density. Its value inside a magnet increases with the h/l ratio. Consequently, bar magnets produce larger and more uniform values than flat magnets. The l/s ratio also influences the magnetic force value in the microchannel, both increasing concomitantly for all the configurations. In addition, a zero force zone in the middle appears in the attraction configuration as the l/s ratio increases, while with a single magnet, the number of maxima and minima goes from one to two, producing two focusing zones instead of only one.; Biochemical Research Methods; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; SCI(E); 0; ARTICLE; 16; 2356-2363; 9
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/246692]  
专题化学与分子工程学院
推荐引用方式
GB/T 7714
Gassner, Anne-Laure,Abonnenc, Melanie,Chen, Hong-Xu,et al. Magnetic forces produced by rectangular permanent magnets in static microsystems[J]. 芯片实验室,2009.
APA Gassner, Anne-Laure.,Abonnenc, Melanie.,Chen, Hong-Xu.,Morandini, Jacques.,Josserand, Jacques.,...&Girault, Hubert H..(2009).Magnetic forces produced by rectangular permanent magnets in static microsystems.芯片实验室.
MLA Gassner, Anne-Laure,et al."Magnetic forces produced by rectangular permanent magnets in static microsystems".芯片实验室 (2009).
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