Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized   Magnetic Nanoparticles

doi:10.1021/bm3007506

CORC > 北京大学 > 化学与分子工程学院

	Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles
	Rouhanifard, Sara H. ; Xie, Ran ; Zhang, Guoxin ; Sun, Xiaoming ; Chen, Xing ; Wu, Peng
刊名	biomacromolecules
	2012
关键词	DC-SIGN TERMINAL ALKYNES T-CELLS CYCLOADDITION VACCINES ANTIGEN AZIDES
DOI	10.1021/bm3007506
英文摘要	dendritic cell (DC)-specific intracellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN) is a receptor found on DCs that recognizes antigens bearing mannose-rich or fucosylated glycans, including Lewis X (Le(X)). Here, we report the fabrication of magnetic nanoparticles coated with multivalent Le(X) glycans using Cu (I)-catalyzed azide-alkyne cycloaddition. The resulting nanoparticles are selective and biocompatible, serving as a highly efficient tool for DC detection and enrichment.; Biochemistry & Molecular Biology; Chemistry, Organic; Polymer Science; SCI(E); EI; 3; ARTICLE; 10; 3039-3045; 13
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/231213]
专题	化学与分子工程学院生命科学学院
推荐引用方式 GB/T 7714	Rouhanifard, Sara H.,Xie, Ran,Zhang, Guoxin,et al. Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles[J]. biomacromolecules,2012.
APA	Rouhanifard, Sara H.,Xie, Ran,Zhang, Guoxin,Sun, Xiaoming,Chen, Xing,&Wu, Peng.(2012).Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles.biomacromolecules.
MLA	Rouhanifard, Sara H.,et al."Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles".biomacromolecules (2012).