傅里叶变换红外光谱体表无创探测乳腺肿瘤

doi:10.7503/cjcu20120410

CORC > 北京大学 > 化学与分子工程学院

	傅里叶变换红外光谱体表无创探测乳腺肿瘤; Surface Noninvasive Detection of Breast Tumors Using Fourier Transform Infrared Spectroscopy
	申伟 ; 赵红梅 ; 雷玉涛 ; 凌晓锋 ; 祝青 ; 张应 ; 张元福 ; 徐怡庄 ; 吴瑾光 ; 武阳丰 ; 李会娟 ; 徐智
刊名	高等学校化学学报
	2012
关键词	傅里叶变换红外光谱衰减全反射光导纤维乳腺癌 Fourier transform infrared (FTIR) spectroscopy Attenuated total reflectance (ATR) Optical fiber Breast cancer
DOI	10.7503/cjcu20120410
英文摘要	利用傅里叶变换红外(FTIR)光谱仪联合衰减全反射(ATR)探头的中红外光导纤维对46名健康志愿者及113名乳腺肿物患者的体表皮肤进行无创红外光谱测定,并从分子水平比较、分析了正常乳腺和有肿物乳腺体表皮肤的红外光谱特征.结果表明,健康志愿者乳房皮肤8个FTIR光谱测定部位的图谱趋于一致；正常乳腺体表与有肿瘤乳腺体表的吸收峰差异明显,而1080 cm-1处核酸相关吸收峰的变化对鉴别肿瘤的良、恶性有重要意义.; To identify Fourier transform infrared (FTIR) spectra of normal and abnormal (mass) breast skin at molecular level, infrared scanning was performed for 46 healthy volunteers and 113 inpatients with palpable breast masses. Breast surface were measured by FTIR spectrometer equipped with attenuated total reflectance (ATR) probe and infrared optical fiber. The results showed that the spectra of healthy volunteers tended to be consistent; the FTIR spectra of control, benign and malignant groups differed owing to content or configuration alterations of nucleic acids, proteins, lipids and carbohydrates, and changes in differential diagnosis of benign and malignant were predominantly observed in the 1080 cm(-1) peak absorbance, commonly associated with nucleic acids.; 中央高校基本科研业务费专项-北京大学临床研究项目; 北京市自然科学基金; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000311593700006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; SCI(E); 中文核心期刊要目总览(PKU); 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); 5; 11; 2390-2396; 33
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/229369]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	申伟,赵红梅,雷玉涛,等. 傅里叶变换红外光谱体表无创探测乳腺肿瘤, Surface Noninvasive Detection of Breast Tumors Using Fourier Transform Infrared Spectroscopy[J]. 高等学校化学学报,2012.
APA	申伟.,赵红梅.,雷玉涛.,凌晓锋.,祝青.,...&徐智.(2012).傅里叶变换红外光谱体表无创探测乳腺肿瘤.高等学校化学学报.
MLA	申伟,et al."傅里叶变换红外光谱体表无创探测乳腺肿瘤".高等学校化学学报 (2012).