直肠癌和直肠正常组织的傅里叶变换红外光谱研究

doi:10.3321/j.issn:1000-0593.2003.03.022

CORC > 北京大学 > 化学与分子工程学院

	直肠癌和直肠正常组织的傅里叶变换红外光谱研究; FTIR Spectroscopic Study of Normal and Malignant Tissues of Rectum
	王凡 ; 凌晓峰 ; 杨展澜 ; 徐智 ; 任予 ; 李维红 ; 翁诗甫 ; 吴瑾光
刊名	光谱学与光谱分析
	2003
关键词	傅里叶变换红外光谱(FTIR) 直肠癌数据分析 FTIR malignant tissues of rectum data-analysis
DOI	10.3321/j.issn:1000-0593.2003.03.022
英文摘要	利用傅里叶变换中红外(FTIR)光纤和ATR技术研究了21例直肠癌病人的正常和癌变组织.对319张光谱进行数据分析的结果表明,五个相对峰高(I2 873/I2 854,I1 745/I1 643,I1 458/I1 400,I1 240/I1 315和I1 162/I1 082,单位为cm-1) 的差别可用于区分直肠癌和直肠正常组织.用这一差别分析了距离直肠癌1cm处组织的光谱,发现该组织处于正常和癌变的过渡状态.; Fourier transform infrared (FTIR) spectroscopy was used to study the normal and malignant tissues of rectum. The FTIR spectra of tissues were measured by Nicolet Magna IR-750 spectrometer equipped with mid-infrared fiber optics. The results show that the intensity ratios of five pairs of bands can be used to distinguish the normal and malignant tissues. In the spectra of malignant tissues the relative intensities ratios of I-2873/ I-2852 and I-1312/ I-1245 were higher than those of normal ones; however, the ratios of I-1 745 / I-1 643, I-1458/I-1400 and I-1162/I-1082 were lower. These results, proved by data-analysis of spectra from 21 patients, were generally shown in the spectra of rectum tissues. The study of near-malignant tissues (one centimeter beside the malignant point) of rectum by FTIR shows that these ratios of bands were in a transient state between normal and malignant rectum tissues.; 国家自然科学基金; 国家重点基础研究发展计划(973计划); 科技部专项基金; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183917000022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; SCI(E); PubMed; 中文核心期刊要目总览(PKU); 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); 13; 3; 498-501; 23
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/200196]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	王凡,凌晓峰,杨展澜,等. 直肠癌和直肠正常组织的傅里叶变换红外光谱研究, FTIR Spectroscopic Study of Normal and Malignant Tissues of Rectum[J]. 光谱学与光谱分析,2003.
APA	王凡.,凌晓峰.,杨展澜.,徐智.,任予.,...&吴瑾光.(2003).直肠癌和直肠正常组织的傅里叶变换红外光谱研究.光谱学与光谱分析.
MLA	王凡,et al."直肠癌和直肠正常组织的傅里叶变换红外光谱研究".光谱学与光谱分析 (2003).