QQ客服 官方微博 反馈留言

	Strategic innovation in the total synthesis of complex natural products using gold catalysis
	Zhang, Yun ; Luo, Tuoping ; Yang, Zhen
	2014
关键词	LYCOPODIUM ALKALOIDS MAGELLANINE CROSS-COUPLING REACTIONS ATROP-ABYSSOMICIN-C SILYL ENOL ETHERS STEREOCHEMICAL ASSIGNMENT BIOLOGICAL EVALUATION ASYMMETRIC-SYNTHESIS FORMAL SYNTHESIS AU CATALYSIS OKADAIC ACID
DOI	10.1039/c3np70075e
英文摘要	Novel organic reactions drive the advance of chemical synthesis in the same way that enabling technologies drive new scientific discoveries. One area of organic methodology that has undergone significant growth during the last decade is that of homogeneous gold-catalyzed transformations. This trend has been further enhanced by the employment of gold catalysis on a routine basis to accomplish the total synthesis of natural products. In particular, the superior p acidity of the cationic gold complex for the activation of alkynes and allenes towards nucleophilic addition has significantly enriched the toolkit of transformations available to the total synthesis community, and inspired a new era of creativity in terms of the strategic disconnection of target compounds during their retrosynthetic analysis. Instead of simply supplementing the many existing reviews of gold catalysis, this review has been organized from the perspective of synthetic target families, with particular emphasis on the use of gold-catalyzed transformations during the late stages of syntheses involving complicated substrates, and cascade reactions that significantly increase molecular complexity.; Biochemistry & Molecular Biology; Chemistry, Medicinal; Chemistry, Organic; SCI(E); PubMed; 12; REVIEW; tuopingluo@pku.edu.cn; zyang@pku.edu.cn; 4; 489-503; 31
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/190285]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhang, Yun,Luo, Tuoping,Yang, Zhen. Strategic innovation in the total synthesis of complex natural products using gold catalysis[J],2014.
APA	Zhang, Yun,Luo, Tuoping,&Yang, Zhen.(2014).Strategic innovation in the total synthesis of complex natural products using gold catalysis..
MLA	Zhang, Yun,et al."Strategic innovation in the total synthesis of complex natural products using gold catalysis".(2014).

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。