Fish in chips: an automated microfluidic device to study drug dynamics   in vivo using zebrafish embryos

doi:10.1039/c3cc47285j

CORC > 北京大学 > 化学与分子工程学院

	Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos
	Zheng, Chunhong ; Zhou, Hongwei ; Liu, Xinxing ; Pang, Yuhong ; Zhang, Bo ; Huang, Yanyi
刊名	chemical communications
	2014
关键词	SMALL-MOLECULE INHIBITORS CYCLOPAMINE CHEMISTRY DISCOVERY PLATFORM SYSTEM
DOI	10.1039/c3cc47285j
英文摘要	Interference of the Hedgehog (Hh) signaling pathway by cyclopamine leads to abnormal embryonic development. We monitor this dynamical drug effect in zebrafish embryos with highly precise microenvironment control using an integrated microfluidic device. This chip-based platform, which is programmable and automated, greatly facilitates the accuracy and reproducibility of the in vivo assays.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000328887400020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; SCI(E); PubMed; 5; ARTICLE; yanyi@pku.edu.cn; 8; 981-984; 50
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/153861]
专题	化学与分子工程学院生命科学学院工学院
推荐引用方式 GB/T 7714	Zheng, Chunhong,Zhou, Hongwei,Liu, Xinxing,et al. Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos[J]. chemical communications,2014.
APA	Zheng, Chunhong,Zhou, Hongwei,Liu, Xinxing,Pang, Yuhong,Zhang, Bo,&Huang, Yanyi.(2014).Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos.chemical communications.
MLA	Zheng, Chunhong,et al."Fish in chips: an automated microfluidic device to study drug dynamics in vivo using zebrafish embryos".chemical communications (2014).