Light and host-guest inclusion mediated salmon sperm DNA/surfactant   interactions

doi:10.1016/j.jcis.2011.06.083

CORC > 北京大学 > 化学与分子工程学院

	Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions
	Lin, Yiyang ; Zhang, Yudong ; Qiao, Yan ; Huang, Jianbin ; Xu, Baocai
刊名	胶体与界面科学杂志
	2011
关键词	DNA complexation Surfactant Light Host-guest interaction Azobenzene CATIONIC GEMINI SURFACTANTS GENOMIC DNA CONFORMATION GENE DELIVERY ALPHA-CYCLODEXTRIN AQUEOUS-SOLUTION PHYSICOCHEMICAL CHARACTERIZATION PHOTOSENSITIVE SURFACTANTS SUPRAMOLECULAR ASSEMBLIES MOLECULAR-MECHANISM BETA-CYCLODEXTRIN
DOI	10.1016/j.jcis.2011.06.083
英文摘要	DNA/cationic surfactant interaction is relevant from the viewpoint of gene therapy, where the complexation and resulting compaction are essential to protect DNA from nuclease, and to allow entry of DNA into cells. In this work, light input and host-guest inclusion controlled DNA complexation by a novel cationic surfactant 1-[6-(4-phenylazo-phenoxy)-hexyl]-3-methylimidazolium bromide (AzoC6Mim) is reported. The surfactant is covalently attached with an azobenzene group, which undergoes reversible photoisomerizations by changing light input. Under visible light, trans-AzoC6Mim can bind to salmon sperm DNA through electrostatic attraction and hydrophobic interaction, resulting into DNA compaction. Under UV light, although cis-AzoC6Mim still binds to DNA chain, DNA/surfactant complex is decompacted owing to the decrease of surfactant hydrophobicity. On the other hand, azobenzene group can form an inclusion complex with alpha-CD through host-guest interaction, which removes AzoC6Mim from DNA chain and decompacts the DNA/surfactant complex. (C) 2011 Elsevier Inc. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000294142500024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Physical; SCI(E); PubMed; 12; ARTICLE; 2; 430-438; 362
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/149949]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Lin, Yiyang,Zhang, Yudong,Qiao, Yan,et al. Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions[J]. 胶体与界面科学杂志,2011.
APA	Lin, Yiyang,Zhang, Yudong,Qiao, Yan,Huang, Jianbin,&Xu, Baocai.(2011).Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions.胶体与界面科学杂志.
MLA	Lin, Yiyang,et al."Light and host-guest inclusion mediated salmon sperm DNA/surfactant interactions".胶体与界面科学杂志 (2011).