pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition

CORC > 金属研究所 > 中国科学院金属研究所

	pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition
	Feng, LJ; Yang, HY; Dong, XQ; Lei, HB; Chen, D; Feng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
刊名	JOURNAL OF APPLIED POLYMER SCIENCE
	2018-02-20
卷号	135 期号:8 页码:-
关键词	Transfer Radical Polymerization Functionalized Graphene Sheets Comb-like Polymers End-use Evaluation Nanocomposites Adhesive Crystallization Oxide Chemistry Mechanism
ISSN号	0021-8995
英文摘要	The waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.; The waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.
学科主题	Polymer Science
语种	英语
资助机构	Project of Shandong Province Higher Educational Science and Technology Program [J15LA62]; Distinguished Middle-Aged and Young Scientist Encourage and Reward Foundation of Shandong Province [BS2014CL029]
公开日期	2018-06-05
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/79492]
专题	金属研究所_中国科学院金属研究所
通讯作者	Feng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
推荐引用方式 GB/T 7714	Feng, LJ,Yang, HY,Dong, XQ,et al. pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(8):-.
APA	Feng, LJ,Yang, HY,Dong, XQ,Lei, HB,Chen, D,&Feng, LJ .(2018).pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition.JOURNAL OF APPLIED POLYMER SCIENCE,135(8),-.
MLA	Feng, LJ,et al."pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition".JOURNAL OF APPLIED POLYMER SCIENCE 135.8(2018):-.