Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing

doi:10.1016/j.msec.2018.08.013

CORC > 金属研究所 > 中国科学院金属研究所

	Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing
	Yan, XD ; Wan, P 1; Tan, LL ; Zhao, MC ; Qin, L 3; Yang, K
刊名	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
	2018-12-01
卷号	93 页码:565-581
关键词	Magnesium alloy Copper Corrosion Processing Antibacterial
ISSN号	0928-4931
DOI	10.1016/j.msec.2018.08.013
英文摘要	Mg-Cu alloys were designed by introducing the well-known antibacterial property of copper into magnesium alloy to solve the infection problem especially under the neutralised environment in vitro. In this paper, the Mg-Cu alloys with further processing by solution and extrusion were studied to optimise the corrosion-related performance for their future application. It was shown that the differences in the property profile of Mg-Cu alloys are dependent on different compositions as well as on different microstructures that are obtained by the different processing routes. Galvanic corrosion can be significantly relieved by solution treatment and extrusion due to decrease and well distribution of cathodic Mg2Cu phases. Negligible cytotoxicity were observed with rBMSCs incubation. Antibacterial assays proved that the alloys reduced the viability of Staphylococcus aureus by high alkalinity and copper ions releasing, especially in comparison with pure magnesium. Finally, the as-solutionized Mg-0.1Cu alloy showed the optimal corrosion properties and promising antibacterial activity, which warranted its potentials as antibacterial biodegradable implant materials.
学科主题	Materials Science, bioMaterials
语种	英语
WOS记录号	WOS:000447569400054
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/79798]
专题	金属研究所_中国科学院金属研究所
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Dongguan Univ Technol, Sch Mech Engn, Dongguan 523808, Peoples R China 3.Cent S Univ, Sch Mat Sci & Engn, Changsha 410083, Peoples R China 4.Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Dept Orthopaed & Traumatol, Hong Kong, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Yan, XD,Wan, P,Tan, LL,et al. Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2018,93:565-581.
APA	Yan, XD,Wan, P,Tan, LL,Zhao, MC,Qin, L,&Yang, K.(2018).Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,93,565-581.
MLA	Yan, XD,et al."Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 93(2018):565-581.