Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants

doi:10.1038/s41477-019-0458-0

CORC > 西双版纳热带植物园 > 中国科学院西双版纳热带植物园 > 2012年后新成立研究组

	Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants
	Yang, Zhenzhen 7; Wafula, Eric K.; Kim, Gunjune 8; Shahid, Saima 9; McNeal, Joel R.; Ralph, Paula E.; Timilsena, Prakash R.; Yu, Wen-bin; Kelly, Elizabeth A.; Zhang, Huiting
刊名	NATURE PLANTS
	2019
卷号	5 期号:9 页码:991-1001
ISSN号	2055-026X
DOI	10.1038/s41477-019-0458-0
英文摘要	Horizontal gene transfer (HGT), the movement and genomic integration of DNA across species boundaries, is commonly associated with bacteria and other microorganisms, but functional HGT (fHGT) is increasingly being recognized in heterotrophic parasitic plants that obtain their nutrients and water from their host plants through direct haustorial feeding. Here, in the holoparasitic stem parasite Cuscuta, we identify 108 transcribed and probably functional HGT events in Cuscuta campestris and related species, plus 42 additional regions with host-derived transposon, pseudogene and non-coding sequences. Surprisingly, 18 Cuscuta fHGTs were acquired from the same gene families by independent HGT events in Orobanchaceae parasites, and the majority are highly expressed in the haustorial feeding structures in both lineages. Convergent retention and expression of HGT sequences suggests an adaptive role for specific additional genes in parasite biology. Between 16 and 20 of the transcribed HGT events are inferred as ancestral in Cuscuta based on transcriptome sequences from species across the phylogenetic range of the genus, implicating fHGT in the successful radiation of Cuscuta parasites. Genome sequencing of C. campestris supports transfer of genomic DNA-rather than retroprocessed RNA-as the mechanism of fHGT. Many of the C. campestris genes horizontally acquired are also frequent sources of 24-nucleotide small RNAs that are typically associated with RNA-directed DNA methylation. One HGT encoding a leucine-rich repeat protein kinase overlaps with a microRNA that has been shown to regulate host gene expression, suggesting that HGT-derived parasite small RNAs may function in the parasite-host interaction. This study enriches our understanding of HGT by describing a parasite-host system with unprecedented gene exchange that points to convergent evolution of HGT events and the functional importance of horizontally transferred coding and non-coding sequences.
学科主题	Plant Sciences
语种	英语
WOS记录号	WOS:000485155000017
内容类型	期刊论文
源URL	[http://ir.xtbg.org.cn/handle/353005/11497]
专题	西双版纳热带植物园_2012年后新成立研究组
作者单位	1.[Yang, Zhenzhen; Shahid, Saima; Kelly, Elizabeth A.; Zhang, Huiting; Axtell, Michael J.; dePamphilis, Claude W.] Penn State Univ, Huck Inst Life Sci, Intercoll Grad Program Plant Biol, University Pk, PA 16802 USA 2.Yang, Zhenzhen; Wafula, Eric K.; Shahid, Saima; Ralph, Paula E.; Timilsena, Prakash R.; Yu, Wen-bin; Kelly, Elizabeth A.; Zhang, Huiting; Axtell, Michael J.; dePamphilis, Claude W.] Penn State Univ, Dept Biol, University Pk, PA 16802 USA 3.Kim, Gunjune; Westwood, James H.] Virginia Polytech Inst & State Univ, Dept Plant Pathol Physiol & Weed Sci, Blacksburg, VA 24061 USA 4.McNeal, Joel R.] Kennesaw State Univ, Dept Ecol Evolut & Organismal Biol, Kennesaw, GA 30144 USA 5.Person, Thomas Nate; dePamphilis, Claude W.] Penn State Univ, Huck Inst Life Sci, Intercoll Grad Program Bioinformat & Genom, University Pk, PA 16802 USA 6.Altman, Naomi S.] Penn State Univ, Dept Stat, University Pk, PA 16802 USA 7.Altman, Naomi S.] Penn State Univ, Huck Inst Life Sci, University Pk, PA 16802 USA 8.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai, Peoples R China 9.Future Technol Corp R&D, Seoul, South Korea 10.Donald Danforth Plant Sci Ctr, St Louis, MO USA
推荐引用方式 GB/T 7714	Yang, Zhenzhen,Wafula, Eric K.,Kim, Gunjune,et al. Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants[J]. NATURE PLANTS,2019,5(9):991-1001.
APA	Yang, Zhenzhen.,Wafula, Eric K..,Kim, Gunjune.,Shahid, Saima.,McNeal, Joel R..,...&dePamphilis, Claude W..(2019).Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants.NATURE PLANTS,5(9),991-1001.
MLA	Yang, Zhenzhen,et al."Convergent horizontal gene transfer and cross-talk of mobile nucleic acids in parasitic plants".NATURE PLANTS 5.9(2019):991-1001.