Investigating the effect of mono- and multivalent counterions on the conformation of poly(styrenesulfonic acid) by nanopores

doi:10.1002/elps.201800539

CORC > 化学研究所 > 中国科学院化学研究所

	Investigating the effect of mono- and multivalent counterions on the conformation of poly(styrenesulfonic acid) by nanopores
	Zhao, Yating; Liu, Lei; Tu, Yingfeng; Wu, Hai-Chen
刊名	ELECTROPHORESIS
	2019-08-01
卷号	40 期号:16-17 页码:2180-2185
ISSN号	0173-0835
DOI	10.1002/elps.201800539
英文摘要	Polyelectrolytes are useful materials that have many technical, medical, physiological and biological applications. The properties of polyelectrolytes are determined not only by their chemical composition but also by their conformational states. However, the conformations of polyelectrolytes in solution are very difficult to characterize. Herein, we propose to use a protein nanopore to investigate the effect of mono- and multivalent counterions on the conformational changes of a simple polyelectrolyte, sodium poly(styrenesulfonic acid) (NaPSS). High concentration of KCl induced a conformational transition of NaPSS from "swollen random coil" form in low salt concentration to "random coil" form and was evidenced by the changes of the translocation event pattern. Addition of Mg2+ in buffer solution did not cause notable changes of NaPSS translocation events, but Dy3+ and Y3+ were shown to have remarkable effects on the translocation profile of NaPSS. Bridging events caused by Dy3+ or Y3+ between polyelectrolyte chains largely affected current blockage and dwell time of the translocation events. Our results provide experimental evidence for the classical theories of conformational transitions of polyelectrolytes and may find applications in many other polyelectrolyte-related researches.
语种	英语
WOS记录号	WOS:000478750500021
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/82704]
专题	中国科学院化学研究所
作者单位	Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Yating,Liu, Lei,Tu, Yingfeng,et al. Investigating the effect of mono- and multivalent counterions on the conformation of poly(styrenesulfonic acid) by nanopores[J]. ELECTROPHORESIS,2019,40(16-17):2180-2185.
APA	Zhao, Yating,Liu, Lei,Tu, Yingfeng,&Wu, Hai-Chen.(2019).Investigating the effect of mono- and multivalent counterions on the conformation of poly(styrenesulfonic acid) by nanopores.ELECTROPHORESIS,40(16-17),2180-2185.
MLA	Zhao, Yating,et al."Investigating the effect of mono- and multivalent counterions on the conformation of poly(styrenesulfonic acid) by nanopores".ELECTROPHORESIS 40.16-17(2019):2180-2185.