Glycosides from roots of Cyathula officinalis Kuan

	Glycosides from roots of Cyathula officinalis Kuan
	Zhou, R ; Li, BG ; Zhang, GL
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2005
卷号	47 期号:3 页码:368_374
关键词	Cyathula officinalis Kuan cytotoxic activity glycoside oleanolic acid
ISSN号	1672-9072
通讯作者	Zhang, GL, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China.
产权排序	1
中文摘要	To search for new and bioactive compounds from traditional Chinese medicines, a new glycoside, 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-(n-butyl-beta-D-glucopyranosiduronate)]-28-O-beta-D-glucopyranosyl oleanolic acid (1), was isolated from the roots of Cyathula officinalis Kuan, along with 3-O-(methyl-beta-D-glucopyranosiduronate)-28-O-beta-D-glucopyranosyl oleanolic acid (2), 3-O-beta-D-glucopyranosyl oleanolic acid (3), 3-O-beta-D-glucuronopyranosyl oleanolic acid (4), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-(beta-D-glucuronopyranosyl)] oleanolic acid (5), 3-O-(beta-D-glucuronopyranosyl)-28-O-beta-D-glucopyranosyl oleanolic acid (6), 28-O-beta-D-glucuronopyranosyl-(1 -> 4)-beta-D-glucopyranosyl hederagenin (7), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-beta-D-glucuronopyranosyl]-28-O-beta-D-glucopyranosyl oleanolic acid (8), and 3-O-[beta-D-glucopyranosyl-(1 -> 3)-beta-D-glucuronopyranosyl]-28-O-beta-D-glucopyranosyl oleanolic acid (9). The structures of these compounds were determined based on spectral and chemical evidence. The 50 per cent growth-inhibiting (GI(50)) of compounds 1 and 5 against MDA-MB-231 (a human breast cancer cell line) was 3.44 x 10(-4) and 4.66 x 10(-4) mol/L, respectively.
学科主题	Biochemistry & Molecular Biology; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000227555900014
公开日期	2011-07-08
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/17647]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Zhou, R,Li, BG,Zhang, GL. Glycosides from roots of Cyathula officinalis Kuan[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2005,47(3):368_374.
APA	Zhou, R,Li, BG,&Zhang, GL.(2005).Glycosides from roots of Cyathula officinalis Kuan.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,47(3),368_374.
MLA	Zhou, R,et al."Glycosides from roots of Cyathula officinalis Kuan".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 47.3(2005):368_374.