Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes

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	Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes
	Liu, C; kzou@ctgu.edu.cn; Dan, FJ; Yang, J; Zou, K; Zhang, YX; Wang, JZ; Wu, J; Zhou, Y
刊名	CHINESE CHEMICAL LETTERS
	2007
卷号	18 期号:10 页码:1239-1242
关键词	Tupistra Chinensis Bak. Furostanol Saponin Cox-2 Folk Medicines
ISSN号	1001-8417
英文摘要	Two furostanol saponins were obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province. Their structures were determinedas (25S)-26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta, 22 alpha, 26-tetrol-3-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (1) and (25R)26-O-(beta-D-glucopyranosyl)-furost-1 beta, 3 beta 22a, 26-tetrol 3-O-beta-D-glucopyranosyl-(l -> 4)-beta-D-glucopyranosyl-(l -> 2)-beta-D-glucopyranoside (2), on basis of chemical and spectroscopic evidences. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophages of the rat abdomen induced by LPS at 20 mu g/mL. (c) 2007 Kun Zou. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
学科主题	Chemistry, Multidisciplinary
URL标识	查看原文
资助项目	广东省海洋药物重点实验室
WOS记录号	WOS:000250494100022
公开日期	2011-07-03
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/5214]
专题	南海海洋研究所_广东省海洋药物重点实验室
通讯作者	kzou@ctgu.edu.cn
推荐引用方式 GB/T 7714	Liu, C,kzou@ctgu.edu.cn,Dan, FJ,et al. Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes[J]. CHINESE CHEMICAL LETTERS,2007,18(10):1239-1242.
APA	Liu, C.,kzou@ctgu.edu.cn.,Dan, FJ.,Yang, J.,Zou, K.,...&Zhou, Y.(2007).Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes.CHINESE CHEMICAL LETTERS,18(10),1239-1242.
MLA	Liu, C,et al."Furostanol saponins with inhibitory action against COX-2 production from Tupistra chinensis rhizomes".CHINESE CHEMICAL LETTERS 18.10(2007):1239-1242.