Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016

doi:10.1039/c8qo01147h

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	Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016
	Liu, Yonghong 1; Luo, Xiaowei 1; Chen, Chunmei 1; Tao, Huaming 2; Lin, Xiuping ; Yang, Bin ; Zhou, Xuefeng
刊名	ORGANIC CHEMISTRY FRONTIERS
	2019
卷号	6 期号:6 页码:736
ISSN号	2052-4129
DOI	10.1039/c8qo01147h
英文摘要	Ten new diketopiperazine alkaloids (DAs, 1-10) along with two known congeners (11-12) were characterized from the marine sponge-derived fungus Aspergillus versicolor SCSIO 41016. Their structures including absolute configurations were determined by spectroscopic analyses, quantum chemical calculations, and X-ray diffraction analysis. Pyranamides A-D (1-4) were obtained as rare 1-oxa-8,10-diazaspiro[5.5]undecane containing diketopiperazine alkaloids, while secopyranamide C (5) was obtained as a tetrahydropyran-ring cleavage derivative. Plausible biosynthetic pathways of 1-12 were postulated. Compounds 7 and 12 exhibited weak cytotoxic activities against ACHN, OS-RC-2, and 786-O cells.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/17877]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位	1.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Southern Med Univ, Sch Tradit Chinese Med, Guangzhou 510515, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yonghong,Luo, Xiaowei,Chen, Chunmei,et al. Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(6):736, 740.
APA	Liu, Yonghong.,Luo, Xiaowei.,Chen, Chunmei.,Tao, Huaming.,Lin, Xiuping.,...&Zhou, Xuefeng.(2019).Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016.ORGANIC CHEMISTRY FRONTIERS,6(6),736.
MLA	Liu, Yonghong,et al."Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016".ORGANIC CHEMISTRY FRONTIERS 6.6(2019):736.