Synthesis and properties of ABA-type triblock copolymers of poly(glycolide-co-caprolactone) (A) and poly(ethylene glycol) (B)

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	Synthesis and properties of ABA-type triblock copolymers of poly(glycolide-co-caprolactone) (A) and poly(ethylene glycol) (B)
	Cai, Q ; Bei, JZ ; Wang, SG
刊名	POLYMER
	2002-06-01
卷号	43 期号:13 页码:3585-3591
关键词	Poly(Glycolide-co-caprolactone) Poly(Ethylene Glycol) Block Copolymer
ISSN号	0032-3861
英文摘要	Poly(glycolide-co-caprolactone) (A)-poly(ethylene glycol) (B) ABA-type triblock copolymers (PGCE) were synthesized by bulk ring opening polymerization, using the hydroxyl endgroups of poly(ethylene glycol) (PEG) as initiator and stannous octoate as catalyst. The resulting copolymers were characterized by various analytical techniques. Gel permeation chromatographic analysis indicated that the polymerization product was free of residual monomers, PEG and oligomers. H-1 NMR and differential scanning calorimeter results demonstrated that the copolymers had a structure of poly(glycolide-co-caprolactone) (PGC) chains chemically attached to PEG segments. All the PGCE copolymers showed improved hydrophilicity in comparison with the corresponding PGC copolymers with the same molar ratio of glycolidyl and caproyl units. The microspheres of PGCE copolymer exhibited rough surfaces quite different from the smooth surface of PGC microspheres. This phenomenon was attentively ascribed to the highly swollen ability of PGCE copolymers and the freeze-drying process in the microspheres fabrication. (C) 2002 Elsevier Science Ltd. All rights reserved.
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000175738500001
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/79509]
专题	中国科学院化学研究所
通讯作者	Wang, SG
作者单位	1.Chinese Acad Sci, PCLCC, Inst Chem, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Cai, Q,Bei, JZ,Wang, SG. Synthesis and properties of ABA-type triblock copolymers of poly(glycolide-co-caprolactone) (A) and poly(ethylene glycol) (B)[J]. POLYMER,2002,43(13):3585-3591.
APA	Cai, Q,Bei, JZ,&Wang, SG.(2002).Synthesis and properties of ABA-type triblock copolymers of poly(glycolide-co-caprolactone) (A) and poly(ethylene glycol) (B).POLYMER,43(13),3585-3591.
MLA	Cai, Q,et al."Synthesis and properties of ABA-type triblock copolymers of poly(glycolide-co-caprolactone) (A) and poly(ethylene glycol) (B)".POLYMER 43.13(2002):3585-3591.