Effect of Selective Solvent Addition Rate on the Pathways for Spontaneous Vesicle Formation of ABA Amphiphilic Triblock Copolymers

doi:10.1021/ja909379y

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	Effect of Selective Solvent Addition Rate on the Pathways for Spontaneous Vesicle Formation of ABA Amphiphilic Triblock Copolymers
	Han, Yuanyuan ; Yu, Haizhou ; Du, Hongbo ; Jiang, Wei 1
刊名	JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
	2010-01-27
卷号	132 期号:3 页码:1144-1150
ISSN号	0002-7863
DOI	10.1021/ja909379y
英文摘要	In this study, the kinetics of vesicle formation of ABA amphiphilic triblock copolymers from an initially homogeneous state was theoretically and experimentally investigated by adding a selective solvent into the system. The pathway of spontaneous vesicle formation depended greatly on the selective solvent addition rate. At a slow addition rate, the pathway followed three stages: (1) the amphiphilic triblock copolymer combined into a large irregular aggregation; (2) the large irregular aggregation broke into big irregular spheres; and (3) some hydrophilic molecules in the big irregular spheres diffused toward the surface, and some hydrophilic molecules diffused toward the center, forming vesicles. However, at a fast addition rate, the pathway was as follows: (1) the amphiphilic triblock copolymer aggregated into many small spheres; (2) the small spheres merged to form rod-like micelles first and then oblate membranes; and (3) the oblate membranes closed up to form vesicles. This pathway difference for vesicle formation can be attributed to the existence of many metastable states in the system. This finding not only provides new insight into the origins of vesicles but also provides further understanding on the self-assembly kinetics of amphiphilic block copolymers in a selective solvent.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000275084700044
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/70389]
专题	中国科学院化学研究所
通讯作者	Jiang, Wei
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Univ, Changchun 130022, Peoples R China
推荐引用方式 GB/T 7714	Han, Yuanyuan,Yu, Haizhou,Du, Hongbo,et al. Effect of Selective Solvent Addition Rate on the Pathways for Spontaneous Vesicle Formation of ABA Amphiphilic Triblock Copolymers[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2010,132(3):1144-1150.
APA	Han, Yuanyuan,Yu, Haizhou,Du, Hongbo,&Jiang, Wei.(2010).Effect of Selective Solvent Addition Rate on the Pathways for Spontaneous Vesicle Formation of ABA Amphiphilic Triblock Copolymers.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,132(3),1144-1150.
MLA	Han, Yuanyuan,et al."Effect of Selective Solvent Addition Rate on the Pathways for Spontaneous Vesicle Formation of ABA Amphiphilic Triblock Copolymers".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132.3(2010):1144-1150.