Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan

doi:10.1007/s11426-009-0274-x

CORC > 化学研究所 > 中国科学院化学研究所

	Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan
	Gu JiangYong 1; Yuan Gu 1; Zhu YongHong 2; Xu XiaoJie 1
刊名	SCIENCE IN CHINA SERIES B-CHEMISTRY
	2009-11-01
卷号	52 期号:11 页码:1871-1878
关键词	Chemical Space Drug-target Space Molecular Docking Computational Pharmacology
ISSN号	1006-9291
DOI	10.1007/s11426-009-0274-x
英文摘要	Computational pharmacological methods were used to study the distribution of 1729 compounds contained in a Chinese medicine, Qishen Yiqi Diwan, in chemical space. The results show that most of these compounds have good drug-like properties. Molecular docking was used to study the interactions between 1729 compounds of Qishen Yiqi Diwan and 26 drug targets related to cardiovascular disease and the distribution of 1729 compounds in drug-target space. The results may shed light on the action mechanism and the search for the active compounds in Qishen Yiqi Diwan.
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000272032700019
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/68637]
专题	中国科学院化学研究所
通讯作者	Xu XiaoJie
作者单位	1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat Chem & Applicat, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Acad Tasly Pharmaceut Co LTD, Tianjin 300410, Peoples R China
推荐引用方式 GB/T 7714	Gu JiangYong,Yuan Gu,Zhu YongHong,et al. Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2009,52(11):1871-1878.
APA	Gu JiangYong,Yuan Gu,Zhu YongHong,&Xu XiaoJie.(2009).Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan.SCIENCE IN CHINA SERIES B-CHEMISTRY,52(11),1871-1878.
MLA	Gu JiangYong,et al."Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan".SCIENCE IN CHINA SERIES B-CHEMISTRY 52.11(2009):1871-1878.